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Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Ulcerative colitis involves immune activation, chronic inflammation, and metabolic issues, some of which persist even during remission.

A young man had vision loss, hair loss, and other symptoms, but tests showed mostly normal results except for slightly high protein in spinal fluid.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Higher CO2 levels help a cyanobacterium grow better by boosting photosynthesis and carbon uptake.

New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.

Zinc is vital for health, and its deficiency can worsen gastrointestinal and liver diseases.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.

m6A deregulation plays a key role in PCOS and could lead to new treatments.

The white wax scale insect's genome shows that complete metamorphosis evolved earlier than thought and highlights differences in male and female development.

Hereditary elliptocytosis causes elongated red blood cells and can lead to mild or no symptoms.

Certain plant compounds can help treat diabetes.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Extracellular vesicles can worsen Alzheimer's but also offer potential for diagnosis and treatment.

Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.

Tithonia diversifolia extract improved digestion but didn't enhance lamb growth.

Calorie restriction changes the elemental and isotopic makeup of mouse hair and bone.

Keratin is crucial for skin barrier formation and affects mitochondrial function.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Targeting specific molecular pathways may improve treatments for chemoresistant cancers.