research BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens
BroadAMP-GPT effectively creates antimicrobial peptides to fight drug-resistant bacteria.
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870-900 / 1000+ resultsresearch A novel PLEC nonsense homozygous mutation (c.7159G > T; p.Glu2387*) causes epidermolysis bullosa simplex with muscular dystrophy and diffuse alopecia: a case report
A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.
research Food-derived Crassostrea gigas peptides self-assembled supramolecules for scarless healing
Pacific oyster peptides may help wounds heal without scars.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research Corticosteroids for the treatment of Duchenne muscular dystrophy
Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.
research Complications of Cushing's syndrome: state of the art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
research Estrogens and aging skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Hormesis and medicine
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss
Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
research MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk
A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
research WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research Self-Activated Electrical Stimulation for Effective Hair Regeneration via a Wearable Omnidirectional Pulse Generator
A wearable device using electric stimulation can significantly improve hair growth.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Minoxidil activates β-catenin pathway in human dermal papilla cells: A possible explanation for its anagen prolongation effect
Minoxidil helps hair growth by activating the β-catenin pathway.
research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables
Mutant mice help researchers understand hair growth and related genetic factors.
research Melanin Pigmentary Disorders: Treatment Update
Treatments for melanin disorders exist, but more effective options needed.
research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
research Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function
Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
research A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle
Blue light promotes hair growth by interacting with specific receptors in hair follicles.
research Emerging nonmetabolic functions of skin fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Targeting lymphoid-derived IL-17 signaling to delay skin aging
Blocking IL-17 signaling may reduce skin inflammation and delay aging.
research Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Microneedle-Based Approaches for Skin Disease Treatment
Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.