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MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

A new test using NOS2 and CCL27 genes can better diagnose and treat psoriasis and eczema.

Treatment with biologic agents can significantly improve psoriasis symptoms, and blood biomarkers could potentially predict individual patient's response to treatment.

New technologies replicate human skin for testing without animals.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

A new genetic variant of Woodhouse-Sakati syndrome was found in two adult sisters in Russia.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.

VESALT improves alopecia areata assessment by including non-scalp areas and is reliable and user-friendly.

A new enzyme, BSSP, is found in high amounts in the hair follicles of nude mice.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

AMH is a reliable marker for diagnosing PCOS.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

miR-200c-3p could help diagnose and treat alopecia areata.

S-Methylmethionine sulfonium can protect skin from UVB damage.

MSUD patients need careful monitoring of amino acids and zinc to prevent severe symptoms.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

Defective protein folding due to a mutation is key in ANE syndrome.

Certain gene variations increase male hair loss risk, influenced by hormone levels.

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.

Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.

Women with PCOS in Bangladesh face significant mental health issues, especially in rural areas.