research Ethanol‐induced elevation of 3α‐hydroxy‐5α‐pregnan‐20‐one does not modulate motor incoordination in rats
Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.
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480-510 / 1000+ resultsresearch Characterizing enteric neurons in dopamine transporter (DAT)‐Cre reporter mice reveals dopaminergic subtypes with dual‐transmitter content
Dopaminergic neurons in the gut have diverse subtypes with different neurotransmitter contents.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders
S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
research NATURAL ANTIVIRALS FOR THE MANAGEMENT OF SARS-COVID-19: A REVIEW
Natural plant compounds may offer safer COVID-19 treatments with fewer side effects.
research Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output
Lower allopregnanolone levels increase stress-related dopamine release in the brain.
research Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers
Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
research Anabolic-androgenic steroids. Mechanism of action and clinical effects
Anabolic-androgenic steroids are dangerous and educating people about their risks is essential.
research ANABOLIC ANDROGENIC STEROID USE DISORDER: A PUBLIC HEALTH ISSUE
Anabolic steroid misuse is a major health issue causing severe health problems and requires better awareness and monitoring.
research The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases
Piper cubeba and Aquilaria sinensis may help prevent or treat prostate issues by balancing hormones.
research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation
Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
research Human Hair in Personal Identification and Documenting Drug and Substance Abuse
Human hair is valuable for identifying people and detecting drug use.
research 477 How Cannabidiol Supports Hair Growth: From Epigenetics to the Scalp Microbiome
CBD can help hair grow by supporting scalp health and reducing inflammation.
research Early postnatal allopregnanolone levels alteration and adult behavioral disruption in rats: Implication for drug abuse
Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.
research (Un)targeted Scanning of Locks of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride
Progesterone boosts alcohol's effect on brain, finasteride counters it.
research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice
Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
research Traditional Uses and Pharmacologically Active Constituents of Dendrobium Plants for Dermatological Disorders: A Review
Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
research PHARMACOGNOSTIC AND PHARMACOLOGICAL ASPECT OF BACOPA MONNIERI - A REVIEW
Bacopa monnieri is a herb used in traditional Indian medicine to enhance memory and treat various conditions.
research Squarticles as the nanoantidotes to sequester the overdosed antidepressant for detoxification
Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.
research Simultaneous Analysis of Biomarkers in Human Hair for Evaluating Chronic Tobacco Smoke Exposure and Stress/Relaxation Using Online In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry
A new method can quickly and accurately measure tobacco exposure and stress using a small hair sample.
research Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants
Related plant species often have similar chemicals and healing properties.
research Biochemical approach on the conservation of drug molecules during hair fiber formation
Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.
research The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches
Adjusting neurosteroid levels may help reduce alcohol withdrawal symptoms.
research Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma
Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
research GC-MS determination of steroids related to androgen biosynthesis in human hair with pentafluorophenyldimethylsilyl–trimethylsilyl derivatisation
The method accurately measures certain steroids in human hair, showing different levels in males and females.
research Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice
Neurosteroid withdrawal increases α4 subunit expression in the hippocampus, which may relate to catamenial epilepsy in women.
research Hormone-dependent medial preoptic/lumbar spinal cord/autonomic coordination supporting male sexual behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Unsaturated Halogenated Hydrocarbons
These chemicals can be toxic, causing health issues like cancer, liver damage, and irritation.
research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.