60 citations
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May 2006 in “Journal of Neurochemistry” Social isolation makes rats more sensitive to alcohol's effects on the brain.
28 citations
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October 2011 in “British Journal of Pharmacology” Midazolam's seizure prevention is partly due to increased neurosteroid production.
60 citations
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December 2013 in “PLoS ONE” EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
December 2004 in “Neuropsychopharmacology” Long-term alcohol exposure alters brain receptor function differently in various brain regions.
2 citations
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June 2018 in “Physiology & behavior” Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
2 citations
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January 2011 in “Andrologia” Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
84 citations
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July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
30 citations
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July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
24 citations
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July 1983 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
5alpha-DHP may be a safe, effective treatment for certain seizures without causing sedation.
20 citations
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June 2022 in “Molecules” Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
88 citations
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January 2004 in “Journal of Neuroscience” Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
18 citations
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September 1972 in “British Journal of Pharmacology” PCPA induces hypersexual behavior in male rats regardless of age or castration status.
5 citations
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December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
22 citations
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July 2010 in “Drug Testing and Analysis” A quick method was developed to detect banned substances in urine for doping control.
19 citations
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January 2011 in “Frontiers in Endocrinology” Social isolation makes mice more sensitive to alcohol's effects on brain function.
March 2024 in “Journal of Pharmaceutical and Sciences” Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.
Bioactive compounds in neurocosmetics can improve skin health and emotional well-being.
April 2026 in “Frontiers in Pharmacology” Many medications may be linked to cognitive disorders, but most lack warnings on labels.
61 citations
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September 2011 in “Pain” PEA reduces pain by increasing neurosteroid synthesis in the spinal cord.
193 citations
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February 2015 in “Nature Communications” Fungi-produced compounds can change plant root growth.
November 2001 in “The Journal of neuropsychiatry and clinical neurosciences/The journal of neuropsychiatry and clinical neurosciences” Divalproex sodium can unexpectedly cause agitation and hyperactivity in some patients.
97 citations
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December 2010 in “Journal of Neuroscience” Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.
52 citations
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May 2011 in “Journal of Neuroendocrinology” PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.
Monocyclic aromatic compounds are important for developing various drugs and treatments.
April 2015 in “The FASEB Journal” Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
46 citations
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April 2008 in “Archives of Dermatological Research” Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.