research An integrative view of mammalian seasonal neuroendocrinology
The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.
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270-300 / 1000+ results research Exploring the Complexities of Atopic Dermatitis: Pathophysiological Mechanisms and Therapeutic Approaches
Atopic dermatitis needs personalized treatment using various therapies, starting with topical corticosteroids.
research Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control
Stress can stop hair growth in mice, and treatments can reverse this effect.
research Modification of the immune system with hydrogen sulfide and cyclosporine A
Age-related immune changes significantly affect disease development in other systems.
research Hair cortisol concentrations in mental disorders: A systematic review
People with depression often have higher hair cortisol levels, while those with PTSD tend to have lower levels, but more research is needed to understand this fully.
research Chronic inflammatory demyelinating polyneuropathy associated with alopecia totalis and Sjögren syndrome
Recognizing the link between certain autoimmune disorders and neurological conditions can improve diagnosis and treatment.
research Editorial: Exploring innovative therapies for rare inflammatory skin diseases
New therapies for rare skin diseases show promise but need more research.
research Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases
Targeted cytokine treatments may help with alopecia areata, but more research is needed.
research Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
research Evidence of a Causal Relationship Between Body Mass Index and Immune-Mediated and Inflammatory Skin Diseases and Biomarkers: A Mendelian Randomization Study
research Topische Immuntherapie mit Diphenylcyclopropenon bei verschiedenen Typen der Alpecia areata: Assoziation zu klinischen Parametern und einem funktionellen Genpolymorphismus des Interleukin-6-Promotors
Topical immunotherapy with DPCP is most effective for certain alopecia areata types, with success linked to age and disease duration, and influenced by a gene polymorphism.
research Increased CRHR1 expression on monocytes from patients with AA enables a pro‐inflammatory response to corticotrophin‐releasing hormone
Higher CRHR1 levels in AA patients lead to increased inflammation.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Insights About a Pandemic: Clinical Approach
The pandemic highlighted the need for accurate information, vaccine development, and adapting to new routines while managing stress and misinformation.
research A computational approach to mechanistic and predictive toxicology of pesticides
Pesticides can cause reproductive and adrenal health issues.
research Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies
Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.
research Alopecia and Mental Health: Psychosocial Burden, Neuroendocrine Mechanisms, and Therapeutic Implications
Alopecia affects mental health, causing depression and anxiety, but new treatments can improve both hair growth and quality of life.
research Nanotechnology-Driven Antioxidants and Immunomodulators for Polycystic Ovary Syndrome (PCOS) Therapy
Nanotechnology offers promising new treatments for PCOS by reducing inflammation and oxidative stress.
research Gut Microbiota and Autoimmune Alopecia Areata: Current Insights from the Literature
Gut microbiota changes might play a role in alopecia areata, and microbiome-targeted treatments show promise.
research A case report of a novel, integrative approach to Hashimoto’s thyroiditis with unexpected results
A 23-year-old woman with Hashimoto’s thyroiditis improved significantly after a 15-month integrative treatment plan.
research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses
Recent selection on immune response genes was identified across seven ethnicities.
research Psoriasis in the limelight: the remarkable career of an old skin disease
Tofacitinib may be an effective and safe treatment for adolescent alopecia areata.
research Alopecia and Mental Health: Psychosocial Burden, Neuroendocrine Mechanisms, and Therapeutic Implications
Alopecia affects mental health, causing depression and anxiety, but new treatments can help improve both hair growth and quality of life.
research Patients' Illness Perception as a Tool to Improve Individual Disease Management in Primary Cutaneous Lymphomas
Understanding patients' views on their illness can help improve their disease management.
research Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Latest Advances in Inflammatory Skin Disease
New technologies help better understand and treat inflammatory skin diseases.
research Kaleidoscope
Countries with stricter cultures had fewer COVID-19 cases and deaths, paranoia is linked to false memories, psychosocial intervention works as well with or without antipsychotic drugs for young people with psychosis, smartphones can detect changes in behavior indicating illness relapse, and recruitment agents show regional and gender biases.
research Clinical Snippets
New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
research Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden
Iron deficiency worsens inflammatory skin diseases by disrupting iron balance and increasing inflammation.
research Diabetes mellitus: interdisciplinary medical, surgical and psychological therapeutic approach
A holistic approach combining medical, surgical, and psychological therapies is essential for effectively managing diabetes.