February 2025 in “Infectious Diseases & Immunity” HHV-6 reactivation may be linked to psychiatric disorders and can improve with antiviral treatment.
1 citations
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August 2023 in “Biomolecules” Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.
24 citations
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January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Diffuse alopecia areata involves more inflammation and higher allergy-related antibodies than patchy types.
3 citations
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June 2022 in “Journal of The American Academy of Dermatology” During the COVID-19 pandemic, more people were diagnosed with stress-related skin conditions like acne and temporary hair loss.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” People with alopecia areata have different blood markers that suggest inflammation and immune system issues compared to healthy individuals.
9 citations
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September 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Certain skin symptoms can indicate underlying body-wide illnesses.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
14 citations
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July 2021 in “Reviews in endocrine and metabolic disorders” SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
100 citations
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May 2003 in “Journal of Neuroscience” Neuroactive steroids affect cocaine's rewarding effects through the ς1 receptor.
June 2020 in “Annals of the Rheumatic Diseases” Patients need better information about the risks of long-term steroid use.
2 citations
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January 2014 in “Elsevier eBooks” The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.
1 citations
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May 2012 in “Hair transplant forum international” Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
November 2023 in “Journal of Investigative Dermatology” Higher inflammation markers are linked to more severe alopecia areata.
December 2025 in “Nature Communications” Blocking IL-17a can improve age-related smell loss in mice.
4 citations
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June 2025 in “Frontiers in Immunology” BAFF-targeted therapies can reduce autoimmune disease activity, but more research is needed for precise treatments.
February 2026 in “International Journal of Clinical Dermatology” Certain probiotics can help improve skin conditions like atopic dermatitis, but more research is needed.
December 2025 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)”
18 citations
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October 2014 in “Experimental Dermatology” Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.
34 citations
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July 2006 in “The Journal of Comparative Neurology” Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.
December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
July 2025 in “Journal of Investigative Dermatology” IL-17 inhibitors are more effective than methotrexate in preventing psoriatic arthritis in psoriasis patients.
49 citations
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March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
55 citations
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October 2015 in “Journal of Investigative Dermatology” Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.
July 2023 in “Journal of the European Academy of Dermatology and Venereology” Anti-IL17A therapy reduced venous leg ulcer size by 64% without major side effects.
4 citations
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August 2024 in “Cells” Inflammasome proteins can predict inflammation and outcomes in aneurysmal subarachnoid hemorrhage.
2 citations
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January 2024 in “European Journal of Case Reports in Internal Medicine” Beau's lines on fingernails might indicate past severe COVID-19 and risk of reinfection.
1 citations
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October 2023 in “European Journal of Dermatology” Combining hair transplantation with PRP is more effective for treating hair loss than hair transplantation alone.
89 citations
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October 1996 in “Dermatologic Clinics” Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
22 citations
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November 2014 in “Psychiatric Clinics of North America” Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.