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research Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development

23 citations , April 2010 in “Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology”

The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.

In Vitro and In Vivo Effects of 17β-N-(4-Phenylcarbamoyl) Androst-4-en-3-one Derivatives as 5α-Reductase Inhibitors on Androgen-Dependent Glands

research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands

September 2020 in “Current Enzyme Inhibition”

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

research Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients

58 citations , April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology”

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Tributyltin Effects on Ocinebrina Aciculata: Imposex Development, Sterilization, Sex Change, and Population Decline

research Tributyltin (TBT) effects on Ocinebrina aciculata (Gastropoda: Muricidae): imposex development, sterilization, sex change and population decline

156 citations , October 1996 in “Science of The Total Environment”

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla

61 citations , December 2001 in “Journal of Investigative Dermatology”

Steroid sulfatase in hair follicles may be a target for treating hair loss.

research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes

86 citations , April 2009 in “Journal of anatomy”

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules

research Morpho‐regulation in diverse chicken feather formation: Integrating branching modules and sex hormone‐dependent morpho‐regulatory modules

13 citations , December 2018 in “Development, Growth & Differentiation”

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

research A Case of Virilizing Brenner Tumor in a Postmenopausal Woman With Stromal Androgenic Activity

6 citations , June 2006 in “International Journal of Gynecological Pathology”

A postmenopausal woman's hormone imbalance and symptoms improved after removing benign ovarian tumors.

research Alopecia associated with strontium ranelate use in a 62-year-old woman

3 citations , April 2012 in “Osteoporosis International”

A woman experienced hair loss after taking strontium ranelate for osteoporosis.

Synthesis of Phenanthridin-3-One Derivatives: Non-Steroidal Inhibitors of Steroid 5-Alpha-Reductase

research Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase

20 citations , June 1995 in “Tetrahedron Letters”

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

research Insights on the mechanical behavior of keratin fibrils

13 citations , May 2016 in “International journal of biological macromolecules”

Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.

research Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile

45 citations , December 2007 in “The FASEB journal”

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size

15 citations , May 2009 in “Steroids”

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Corrigendum to Patients Treated for Male Pattern Hair Loss With Finasteride Show, After Discontinuation of the Drug, Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma

research Corrigendum to “Patients treated for male pattern hair loss with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma” [J. Steroid Biochem. Mol. Biol. 146 (2015) 74–79]

September 2023 in “The Journal of Steroid Biochemistry and Molecular Biology”

Stopping finasteride for male pattern hair loss changes neuroactive steroid levels in the brain and blood.

research FINASTERIDE AND PSA

November 2005 in “The Journal of Urology”

Evaluation of New Pregnane Derivatives as 5α-Reductase Inhibitors

research Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.

23 citations , January 2001 in “Chemical & Pharmaceutical Bulletin”

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

$Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]$

research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt₂Cl₄(NH₃)₂{μ-HN=C(O)Bu^t}₂]

2 citations , November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials”

A new platinum complex was made and studied, which might help fight cancer better.

research ELECTRON MICROSCOPE STUDIES OF HAIR AND WOOL

191 citations , November 1959 in “Annals of the New York Academy of Sciences”

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

research LC‐MS/MS‐based method for long‐term steroid profiling in human scalp hair

134 citations , March 2015 in “Clinical Endocrinology”

A new method accurately measures long-term steroid levels in human hair.

research Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex

77 citations , April 2005 in “Journal of Investigative Dermatology”

Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.

research Hypertrichose

September 2001 in “Swiss Medical Forum ‒ Schweizerisches Medizin-Forum”

research Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia

5 citations , April 2023 in “Pharmaceuticals”

The new delivery system improved hair growth in alopecia treatment.

research Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces

23 citations , January 2015 in “Stem cells international”

Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.

3a-Phenylhexahydropentalene-1,6-Dione Synthesis

research 3a-Phenylhexahydropentalene-1,6-dione

March 2026 in “Molbank”

A rigid compound with a common structural motif was successfully synthesized.

research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

2 citations , January 1993

Trichohyalin is a versatile protein involved in hair and skin structure.

research Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle.

March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Beard hair medulla cells have a unique and varied keratin pattern.

research The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats

31 citations , February 1972 in “Experientia”

The diphosphonate was the most effective at preventing calcification in rats.

research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors

20 citations , March 2005 in “Current Medicinal Chemistry”

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

research 13-cis-Retinoic Acid Affects Sheath-Shaft Interactions of Equine Hair Follicles in Vitro

30 citations , February 1996 in “Journal of Investigative Dermatology”

research Identification and Characterization of Two Se6OMTs from Stephania epigaea Offer Novel Insights into the Biosynthetic Pathway of Cepharanthine

3 citations , February 2025 in “Metabolites”

The research found enzymes in Stephania epigaea that help make cepharanthine.

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