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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

PCPA induces hypersexual behavior in male rats regardless of age or castration status.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Potential androgen excess signs vary by demographics and health, needing inclusive evaluation.

Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.

Hair can effectively measure DHEA and testosterone levels in children.

Non-classical 21-hydroxylase deficiency can be missed in newborn screenings and should be considered in cases of early puberty or virilization.

Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.

Male pattern hair loss may be linked to the developmental origins of hair follicles.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

Growth hormone therapy boosts androgen effects on skin in men.

A 5-year-old girl with McCune-Albright syndrome grew abnormal hair due to the drug tamoxifen.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

A 10-year-old boy had the earliest reported case of hair that became progressively kinkier but eventually returned to normal on its own.

A 15-year-old girl with rare reproductive disorders received hormone therapy to develop secondary sexual traits, but infertility persisted.

Women with congenital adrenal hyperplasia showed no prostatic growth.

Finasteride helps treat hair loss and prostate issues by blocking a hormone.

Hyperthyroidism can hide signs of high androgen levels in females.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

Hirsutism in young girls can have causes other than PCOS, so diagnoses should be reassessed if treatments don't work.

Teen hair loss is common, can be caused by genetics or health issues, and can be diagnosed and treated.

Hair cortisol levels in children increase with age but are not affected by gender, puberty, or hair care.

Endocrine diseases in children can cause various skin and hair changes.

A 3.75-year-old girl showed that different body organs can grow at different rates.

Diagnosing and treating PCOS in young people is difficult.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Hair growth and pigmentation in mice involve specific stages crucial for research.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Early diagnosis and personalized treatment are crucial for managing hair loss in children.