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Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

During puberty, hormone levels rise, with early increases in some steroids and most menstrual cycles becoming regular by six years after menarche.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.

Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Delayed puberty affects some teens, and early treatment with hormones can help improve their growth and social well-being.

Delayed puberty often runs in families, can affect growth, and may need hormone treatment.

Higher DHT levels are linked to more acne in adolescents, especially boys.

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.

Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.

Some autistic children may have higher levels of male hormones, which could be linked to aggression.

African-American girls tend to start puberty earlier than white girls, possibly due to increased androgen production.

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

Testosterone affects stress hormone levels differently in adolescent and adult male rats.

Recombinant gonadotropins improve future fertility in CHH patients.

Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.

PCOS is a complex condition that can lead to serious health issues, but early diagnosis and treatment can reduce these risks.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

PCOS is a common condition in women that can lead to infertility and other health issues, and it's diagnosed by specific criteria with various treatment options available.

Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Gynecomastia and premature thelarche often resolve naturally but need evaluation to rule out serious issues.

Stopping the drug usually helps, but tamoxifen or surgery may be needed if symptoms persist.