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Recurrent vaginal bleeding in young girls without puberty signs may require a genital exam to find hidden causes.

A rare ovarian tumor caused early puberty in a 3-year-old girl.

Androgen levels increase with puberty and are linked to sexual hair development.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Adrenal androgens are important for puberty and are influenced by genetics.

Early exposure to fluoride, lead, and certain nutrients affects puberty differently in boys and girls.

Higher childhood DHEAS levels are linked to advanced puberty and DNA changes.

Early diagnosis and personalized treatment of Hashimoto thyroiditis can improve growth and development in children.

Early diagnosis and personalized treatment improve growth and development in children with Hashimoto thyroiditis.

A fungal infection can look like a different scalp condition in teens, leading to wrong treatment until proper tests are done.

Testosterone and letrozole treatment speeds up puberty in boys with delayed development.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.

Precocious puberty is starting earlier due to factors like obesity and chemicals, with treatment focusing on preserving height and addressing social issues.

A young girl had a hormone-secreting tumor removed, leading to decreased hormone levels, but ongoing monitoring is needed.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

During puberty, hormone levels rise, with early increases in some steroids and most menstrual cycles becoming regular by six years after menarche.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.

Canrenone effectively reduced hair growth and testosterone levels in women with excessive hairiness.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Delayed puberty affects some teens, and early treatment with hormones can help improve their growth and social well-being.

Delayed puberty often runs in families, can affect growth, and may need hormone treatment.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.