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The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

A new compound effectively inhibits human 5α-reductase 1.

Epristeride's metabolism in zebrafish helps improve doping detection methods.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Rosary Pea has medicinal benefits but requires careful handling due to its toxicity.

Trazodone and Chlorpromazine might help treat sexual dysfunction from finasteride and SSRIs.

Mice hair follicles take in the amino acid cystine.

The combination of a plant extract and a peptide can increase hair pigmentation and may reverse greying.

Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.

Peperomia pellucida is safe to eat and has strong antioxidant benefits.

Finasteride breaks down into new compounds under acidic conditions.

High doses of Tridax procumbens extract can be toxic, affecting liver and kidneys.

Polyamines, especially spermidine, are essential for hair growth.

A new gene mutation causes hereditary coproporphyria with reduced enzyme activity.

A3B5 can reduce skin pigmentation and slow melanoma growth.

Hair follicles have an enzyme that converts arginine to citrulline in proteins.

Pine resin and abietic acid were found to promote hair growth in mice.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Argininosuccinic aciduria can cause hair loss.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Phenolic compounds from Quercus acutissima leaves, especially casuarinin, may help treat acne.

Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.

New drug uses show promise but need more research.

Progesterone and allopregnanolone increase glycine release in rat brain cells.

Finasteride forms three new products under acidic stress.

Tridax procumbens flower extracts can kill bacteria.

Mutations in the P2RY5 gene cause hereditary woolly hair.