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GlossaryQuantitative Analysis

process of using numerical data to measure and evaluate variables

Quantitative Analysis refers to the process of using numerical data to measure and evaluate variables. In the context of hair and alopecia, it might involve counting the number of hair strands lost per day or measuring the density of hair follicles in a given scalp area. This method provides objective, measurable results that can be statistically analyzed to identify patterns or assess the effectiveness of treatments.

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research Matrix matching in quantitative bioanalysis by LC–MS/MS a dream or a reality?

2 citations , December 2019 in “Bioanalysis”

Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.

research Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry

22 citations , January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

A new method accurately measures nine specific hormones in human blood.

Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative analysis of finasteride tablets dissolution content with non-isotopically labeled internal standard by paper spray ionization mass spectrometry

2 citations , September 2018 in “Journal of Separation Science”

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

research LC–MS bioanalytical method for simultaneous determination of latanoprost and minoxidil in the skin

9 citations , May 2020 in “Journal of Pharmaceutical and Biomedical Analysis”

Method measures latanoprost and minoxidil in skin accurately and precisely.

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

823 citations , February 1998 in “Analytical Chemistry”

Method detects finasteride in plasma at very low concentrations.

research Nanozymes expanding the boundaries of biocatalysis

85 citations , July 2025 in “Nature Communications”

Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.

research A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair

7 citations , April 2022 in “Journal of pharmaceutical and biomedical analysis”

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

research Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications

November 2025 in “Molecules”

Microextraction techniques improve hormone testing while being environmentally friendly.

research The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19

8 citations , July 2023 in “Frontiers in Pharmacology”

Cepharanthine shows promise as a COVID-19 treatment.

research Pyrene Excimer Nucleic Acid Probes for Biomolecule Signaling

40 citations , October 2009 in “Journal of Biomedical Nanotechnology”

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

research High resolution full scan liquid chromatography mass spectrometry comprehensive screening in sports antidoping urine analysis

49 citations , December 2017 in “Journal of pharmaceutical and biomedical analysis”

The method effectively detects banned substances in urine for sports antidoping.

research Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma

1 citations , October 2023 in “European journal of histochemistry”

Ozone and procaine boost the release of healing factors in platelet-rich plasma.

research Rapid determination of finasteride in human plasma by UPLC–MS/MS and its application to clinical pharmacokinetic study

18 citations , April 2010 in “Journal of Chromatography B”

New method measures finasteride in blood quickly and accurately.

research Elemental hair analysis: A review of procedures and applications

96 citations , September 2017 in “Analytica Chimica Acta”

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Development of a Spectrophotometric Method to Determine Minoxidil by Diazotization-Coupling Reaction with Sulfanilic Acid

research Development of a Spectrophotometric Method to determination Minoxidil by Diazotization-Coupling reaction with Sulfanilic acid

June 2025 in “Samarra Journal of Pure and Applied Science”

A new method accurately measures minoxidil in tablets.

Herbal Hair Gel Formulation with 5α-Reductase Inhibitory Activity and Standardization by HPTLC

research Herbal Hair Gel Formulation having 5α-Reductase Inhibitory Activity and its Standardization by HPTLC

4 citations , January 2016 in “Journal of analytical & bioanalytical techniques”

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Protein Disulfide Isomerase-Mediated Grafting of Cysteine-Containing Peptides onto Over-Bleached Hair

research Protein disulphide isomerase-mediated grafting of cysteine-containing peptides onto over-bleached hair

28 citations , December 2011 in “Biocatalysis and biotransformation”

PDI helps restore over-bleached hair's strength and structure by attaching special peptides.

HPTLC Method Validation for Simultaneous Determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form

research HPTLC Method Validation for simultaneous determination of Tamsulosin Hydrochloride and Finasteride in Bulk and Pharmaceutical Dosage Form

14 citations , January 2011 in “Journal of analytical & bioanalytical techniques”

Created accurate method to measure tamsulosin hydrochloride and finasteride in tablets.

Analysis of Hormone Antagonists in Clinical and Municipal Wastewater by Isotopic Dilution Liquid Chromatography Tandem Mass Spectrometry

research Analysis of hormone antagonists in clinical and municipal wastewater by isotopic dilution liquid chromatography tandem mass spectrometry

51 citations , February 2010 in “Analytical and Bioanalytical Chemistry”

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-Sulfonate

research Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-sulfonate (NQS)

4 citations , January 2015 in “Journal of analytical & bioanalytical techniques”

New method accurately measures finasteride in medicine using NQS.

research Matrix effects and application of matrix effect factor

323 citations , November 2017 in “Bioanalysis”

Matrix effects in LC-MS can be managed but not completely avoided.

research Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors

7 citations , February 2020 in “Analytical and Bioanalytical Chemistry”

research Untargeted hair lipidomics: comprehensive evaluation of the hair-specific lipid signature and considerations for retrospective analysis

4 citations , July 2023 in “Analytical and Bioanalytical Chemistry”

Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness

research Separation of finasteride and analogues

11 citations , November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Finasteride and analogues separated using LC-MS-MS technique.

Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry

research Selective and rapid determination of tadalafil and finasteride using solid phase extraction by high performance liquid chromatography and tandem mass spectrometry

9 citations , February 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

Quick, selective detection of tadalafil and finasteride in human plasma developed.

research Measurement of Steroid Hormones in Hair: an Analysis of Hormone Dynamics in Hair Follicles

January 2024 in “Institutional Repositories DataBase (IRDB)”

The method accurately measures steroid hormones in hair to study hormone dynamics related to hair loss.

Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine

research Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine

31 citations , February 2019 in “International Journal of Cosmetic Science”

Caffeine applied to the scalp can protect hair follicles from UV damage.