164 citations
,
February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
78 citations
,
June 2013 in “Science” Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.
November 2020 in “Research Square (Research Square)” Chronic scarring alopecia is common in SLE patients and needs early detection and management.
56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
January 2025 in “JCEM Case Reports” Diagnosing and managing Glucocorticoid Resistance Syndrome is complex due to genetic differences and varied symptoms.
2 citations
,
August 2014 in “Journal of the American Academy of Dermatology” A rare case of scleredema in a diabetic woman showed loss of sweat glands, causing heat strokes, with treatment only slightly improving symptoms.
October 2012 in “Institutional Repositories DataBase (IRDB)” Stem cell treatment can effectively regrow hair.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Axolotls regenerate their spinal cord through a signal that recruits cells, influenced by cell sensitivity and signal spread.
36 citations
,
August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
September 2016 in “Journal of dermatological science” TSC2 is crucial for proper hair follicle development and patterning.
ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Rose stem cell nanoparticles improve skin quality by boosting collagen, aiding cell movement, reducing melanin, and lowering inflammation.
January 2025 in “American Journal of Stem Cells” Melanocyte stem cells hold promise for skin regeneration and treating pigmentation issues.
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
41 citations
,
October 2019 in “Biomolecules” Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.
30 citations
,
June 2010 in “Endocrine Related Cancer” SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.
July 2020 in “Research Square (Research Square)” A 3D co-culture model improved stem cell function and wound healing.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
1 citations
,
January 2004 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” SPARC likely aids in tissue remodeling during the hair cycle, not in starting new hair growth phases.
14 citations
,
January 2003 in “Skin Research and Technology” The new scalp coverage scoring method accurately measures hair loss and growth in men.
January 2021 in “European Journal of Molecular & Clinical Medicine” 2 citations
,
May 2024 in “International Journal of Molecular Sciences” Targeting CD169+ skin macrophages may help treat psoriasis.
June 2024 in “Nature Cell and Science” The Scalp Coverage Scoring method reliably measures hair density from images.
67 citations
,
December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
1 citations
,
July 2008 in “PubMed” Human hair keratin helps regenerate rat sciatic nerves by transforming Schwann cells and protecting axons.
29 citations
,
March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
July 2024 in “JAAD Case Reports” Corticosteroid injections for hair loss may cause eye problems, so caution is needed.
1 citations
,
January 2021 in “Arthritis Research & Therapy” About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.
6 citations
,
July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
October 2020 in “Plastic Surgery” Bone marrow stem cells improve healing of deep skin wounds.