research Infertility: Evaluation and Initial Management
Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.
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research Colorimetry provides a rapid objective measurement of de novo hair growth rate in mice
Colorimetry can accurately measure hair growth rates in mice.
research Complementary evolution of coding and noncoding sequence underlies mammalian hairlessness
Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
research Evaluation and Management of the Hair Loss Patient in the Primary Care Setting
Doctors should diagnose hair loss by examining the patient and possibly doing tests, and then treat it based on the type, which may prevent permanent hair loss.
research The evaluation and treatment of androgen excess
High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.
research Histopathological Evaluation of Human Placental Extract as a Direct Pulp-Capping Material in Dogs' Teeth
Human placental extract may be better for tooth repair than current materials.
research Factorial Design-Based Development and Evaluation of Metformin Hydrochloride-Loaded Mucoadhesive Microspheres for Sustained Anti Hyperglycaemic and Anticancer Activity
The developed microspheres effectively deliver Metformin for sustained blood sugar control and anticancer effects.
research Evaluation of ozonated oil and centella asiatica extract on excisional wound healing in Mice
Ozonated oil and Centella asiatica extract improve wound healing in mice, with each having specific benefits.
research Evaluation of microneedling in the treatment of frontal fibrosing alopecia
Microneedling may improve quality of life and reduce inflammation in frontal fibrosing alopecia.
research Evaluating Testosterone and Dehydroepiandrosterone Sulfate (DHEA-S) as Biomarkers for Male Androgenetic Alopecia
Higher testosterone and DHEA-S levels may be linked to male pattern baldness.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research Evaluation of the phenotypic, proliferative and secretory profile of mesenchymal stem cells from adipose tissue captured by laser-assisted liposuction
Mesenchymal stem cells from laser-assisted liposuction are as effective and safe as those from conventional liposuction for cell therapy.
research Genome scan for signatures of adaptive evolution in wild African goat (capra nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research WNT10B (wingless-type MMTV integration site family)
WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Evaluation of Eclipta alba L. selections for higher biomass and bioactive compound
Eclipta alba IIHR Sel EA 43 is best for large-scale cultivation due to high growth, yield, and wedelolactone content.
research Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
research Dietary vitamin A regulates wingless-related MMTV integration site signaling to alter the hair cycle
Eating vitamin A affects hair growth and health by changing cell signals in mice.
research Skin aging: mechanisms, evaluation, and rejuvenation
Skin aging can be slowed by targeting cells, hormones, and the microbiome.
research Clonal expansion from standing genetic variation underpins the evolution of an emerging plant pathogen in Australia
The plant pathogen in Australia evolves through existing genetic variation, not new genotypes.
research Androgenetic, Diffuse and Senescent Alopecia in Men: Practical Evaluation and Management
The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.
research Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2
Cepharanthine and Trifluoperazine are effective against SARS-CoV-2.
research Clinical efficacy of silk sericin dressing with collagen for split-thickness skin graft donor site treatment
Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.
research Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted 99mTc-Radioimaging Agents
Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment
Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
research Systematically optimized coenzyme q10-loaded novel proniosomal formulation for treatment of photo-induced aging in mice: characterization, biocompatibility studies, biochemical estimations and anti-aging evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research Concordance Among In-Vivo Reflectance Confocal Microscopy, Trichoscopy, and Histopathology in the Evaluation of Alopecia Areata Incognita
Reflectance confocal microscopy is a promising non-invasive tool for diagnosing alopecia areata incognita.
research Editor's Mailbox
Robert T. Leonard Jr. disagrees with Max Rubin's negative views on hair loss treatment, advocating for hormonal tests in women and supporting the use of medications and surgery for androgenetic alopecia.
research Related Topic: Drug Permeation Through Hair Follicles
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.