research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
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research Acanthosis nigricans, insulin resistance and cutaneous virilism
The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice
CD34 is crucial for skin tumor development in mice.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Integrin signalling regulates YAP/TAZ to control skin homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development.
EGFR is essential for normal hair development and follicle differentiation.
research Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis
Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
research Elevated Circulation Levels of an Antiangiogenic SERPIN in Patients with Diabetic Microvascular Complications Impair Wound Healing through Suppression of Wnt Signaling
High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
research Role of Endolysosomes in Severe Acute Respiratory Syndrome Coronavirus-2 Infection and Coronavirus Disease 2019 Pathogenesis: Implications for Potential Treatments
Targeting endolysosomes may help treat COVID-19.
research Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis
research β-catenin-mediated hair growth induction effect of 3,4,5-tri-O-caffeoylquinic acid
3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.
research Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal?
Enhancing antioxidant responses can improve treatments for various diseases.
research MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Colchicine in Managing Skin Conditions: A Systematic Review
Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.
research Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis
Activating Notch signaling can kill basal cell carcinoma cells.
research A Screen for Key Genes and Pathways Involved in High-Quality Brush Hair in the Yangtze River Delta White Goat
Certain genes and pathways are crucial for high-quality brush hair in Yangtze River Delta White Goats.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research Thymosin Beta-4 Induces Mouse Hair Growth
Thymosin beta-4 promotes hair growth in mice.
research Perspectives on miRNAs Targeting DKK1 for Developing Hair Regeneration Therapy
Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
research Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
research Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review
research Valorization of Hom Thong Banana Peel (Musa sp., AAA Group) as an Anti-Melanogenic Agent Through Inhibition of Pigmentary Genes and Molecular Docking Study
Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.
research Prolactin: A Mammalian Stress Hormone and Its Role in Cutaneous Pathophysiology
Prolactin affects skin health and may lead to new treatments for skin and hair issues.
research Can Pension Funds Partially Manage Longevity Risk by Investing in a Longevity Megafund?
Investing in a longevity megafund can help pension funds reduce longevity risk.
research Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Hair Follicles as Micro-Organs: MicroRNA-Mediated Control of Growth, Cycling, and Fiber Traits
MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.