35 citations
,
September 1972 in “Journal of Biological Chemistry” Steroid hormone binding in rat skin varies with pH, heat, and hair cycle phases.
9 citations
,
March 1993 in “Biochemical Pharmacology” Rat skin can convert minoxidil into its active form, aiding hair growth.
8 citations
,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
5 citations
,
August 2005 in “Anatomy and Embryology” Rat skin has a linear system of nerve fibers linked to hair follicles and muscles.
3 citations
,
October 1979 in “Laboratory animals” Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.
1 citations
,
October 2010 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” The skin fully recovered after using the optical clearing agent, showing no long-term harm.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
21 citations
,
September 2008 in “Magnetic Resonance Imaging” MRI can effectively image skin structures noninvasively.
6 citations
,
May 2009 in “Cell transplantation” Green tea component EGCG helps keep rat skin grafts viable longer.
9 citations
,
June 2020 in “European Radiology Experimental” 15-Gy x-ray irradiation temporarily alters rat calvaria skin without causing significant inflammation or fibrosis.
41 citations
,
April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
23 citations
,
July 1979 in “Canadian journal of biochemistry” Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.
11 citations
,
January 1976 in “International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine” X-irradiation reduces collagen in rat skin, causing delayed skin damage.
11 citations
,
January 1957 in “Journal of Histochemistry & Cytochemistry” Ca 45 mainly enters rat skin and eye through biosynthesis and may be adsorbed in cartilage and glands.
6 citations
,
September 2012 in “Aesthetic Plastic Surgery” Minoxidil applied before and after surgery improves skin flap survival in rats.
3 citations
,
October 2020 in “Internatuinal Journal of Radiation Research” Gamma irradiation can stimulate hair growth by promoting new blood vessel formation.
1 citations
,
March 2014 in “Applied Microscopy” CK19 and Vimentin are proteins found in rat skin that help with skin renewal and maintaining cell structure.
1 citations
,
June 2000 in “PubMed” Osteopontin may help hair follicle growth during the catagen phase.
33 citations
,
August 1993 in “FEBS Letters” A new enzyme in rats may help regulate hair growth.
6 citations
,
July 1994 in “Journal of Dermatological Science” Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.
June 2026 in “Reports of Morphology” A nutrient-rich diet improved skin and hair health in stressed rats.
1 citations
,
June 2023 in “Acta veterinaria” Maternal hypothyroidism harms skin development in rat offspring.
May 2016 in “Research opinions in animal & veterinary sciences” Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.
August 1969 in “Archives of Dermatology” After calciphylaxis, rats showed incomplete skin and hair regeneration, resembling scar tissue with fewer hairs.
January 2024 in “Journal of developmental biology” Abdominal skin heals faster than dorsal skin because it has more stem cells.
11 citations
,
January 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Silymarin improved wound healing and skin regeneration in rats.
11 citations
,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
2 citations
,
March 2015 in “Human & Experimental Toxicology” Hyperbaric oxygen therapy significantly altered rat facial skin structure.
January 2025 in “International Journal Of Scientific Advances” Topical testosterone can cause acne-like skin changes.
May 2023 in “Current Applied Science and Technology” Higher power CO2 laser causes more severe skin burns and damage.