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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

GI197111X is best dissolved in Capmul MCM for trials.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.

A man got a rare rash from the drug topiramate, which went away after he stopped taking it.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Bexarotene gel shows promise as a new treatment for alopecia areata.

Lurasidone is effective for bipolar depression and schizophrenia, but more safety data is needed.

Peripheral treatments showed some improvement in sexual dysfunction, but central symptoms remain challenging.

Escitalopram helped a woman with hair-pulling due to long COVID.

Ritlecitinib improved hair regrowth and emotional well-being in some alopecia areata patients.

Ritlecitinib helped most alopecia areata patients regrow hair by Week 48.

Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.

Testosterone increases seizure risk through its conversion to specific neurosteroids.

Zinc supplements may help reduce hair loss caused by levetiracetam without affecting seizure control.

Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.

Botulinum neurotoxin injections into the pelvic muscles successfully prevented priapism relapse for over six months.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Oncology specialists are disappointed by the discontinuation of the effective lymphoma treatment Bexxar.

Combining α1A-blockers with Prozac is more effective for treating premature ejaculation than Prozac alone.

Finasteride helps brain function in rats with liver-related brain issues.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

The combination therapy effectively treats infertility in PCOS without major side effects.