418 citations
,
January 2018 in “Journal of Investigative Dermatology” Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
55 citations
,
April 2015 in “BMC medicine” Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
49 citations
,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
30 citations
,
February 2023 in “Journal of Investigative Dermatology” OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
9 citations
,
September 2022 in “Journal of Clinical Investigation” Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
5 citations
,
January 2025 in “Burns & Trauma” Machine learning and single-cell analysis improve understanding and treatment of wound healing.
3 citations
,
December 2023 in “Cell proliferation” Stuff from umbilical cord stem cells helps skin heal and look younger.
2 citations
,
September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
March 2026 in “Preprints.org” The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
Transplanting cultured skin sheets improved acne scars in four patients.
June 2025 in “Cell Metabolism” Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
48 citations
,
January 2018 in “Stem Cells International” Skin-derived stem cells show promise for improving wound healing and creating transplantable tissue.
39 citations
,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
22 citations
,
July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
15 citations
,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
10 citations
,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
4 citations
,
January 2025 in “The Journal of Cell Biology” Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.
7 citations
,
March 2025 in “Free Radical Biology and Medicine” Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
176 citations
,
February 2006 in “Cancer Research” Patched1 helps prevent tumors by controlling cell growth.
105 citations
,
December 2017 in “Journal of Biological Engineering” Artificial skin grafts face immune rejection, but stem cells may improve future designs.
94 citations
,
December 2018 in “Dentistry Journal” Oral-derived stem cells can effectively regenerate bone and tissues in dental procedures.
39 citations
,
April 2023 in “Science Advances” CD34+ cells help heal damaged limbs by promoting blood vessel growth.
12 citations
,
January 2014 in “Journal of international medical research” Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.
6 citations
,
May 2021 in “Aesthetic Surgery Journal” Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
1 citations
,
February 2020 in “Regenerative Medicine” Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.
December 2025 in “Medical Sciences” Regenerative therapies show promise for hair regrowth, but more research and standardization are needed.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” GATA6 is important for maintaining and differentiating cells in a key area of human skin.
97 citations
,
March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause a severe form of brittle hair and skin issues.