research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
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research Platelet-Rich Fibrin
Platelet-rich fibrin helps in healing and rejuvenation but results vary and can take time.
research Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
research 16. Condition-Specific Rhytidectomy: An Evidence-Based Paradigm Shift in Facial Rejuvenation
Tailoring facelift techniques to individual needs improves patient satisfaction.
research 1331 Glutathione (GSH) distribution by quantitative MALDI imaging in reconstructed human skin upon activation of GSH biosynthesis by Nrf2 pathway activator
Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.
research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
research Knowledge Mapping of Drug Repositioning’s Theme and Development
Drug repositioning can save time and money but needs more support.
research Utilização do Plasma Rico em Plaquetas em Procedimentos Estéticos para Rejuvenescimento da Pele: Revisão de ensaios clínicos
PRP combined with other treatments shows promise for skin rejuvenation.
research Sequential immunotherapy for alopecia areata: phase-driven immune rebalancing
Sequential immunotherapy can effectively treat alopecia areata by managing inflammation and promoting hair regrowth.
research Looking Beyond PRP, Exosomes, and Stem Cells
Stem cells, PRP, and exosomes show promise in treating skin conditions but face regulatory and safety challenges.
research A Retrospective Study on the Use of Dermis Micrografts in Platelet-Rich Fibrin for the Resurfacing of Massive and Chronic Full-Thickness Burns
The PRF/micrograft spray-on skin method effectively healed massive and chronic burns quickly.
research Hair Follicle Companion Layer: Reacquainting an Old Friend
research Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using semi-automated processes with custom-coded software
Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Platelet-rich plasma for facial rejuvenation: An early examination
PRP shows promise for skin rejuvenation but needs more research.
research PRP for skin rejuvenation
PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.
research Supercharged Mechanical Stromal-Cell Transfer (MEST)
The MEST method increases cell yield and volume for regenerative medicine but needs more testing.
research New product intros (finasteride/tadalafil (new combination); sutimlimab; human SARS-CoV-2 recombinant nanoparticle vaccine, adjuvanted with AS03; bupropion hydrochloride/dextromethorphan hydrobromide (new combination))
research Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex
Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.
research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis
DRDE-07 shows promise for treating skin diseases due to its favorable properties.
research 578 Addressing the missing components for appropriate surveillance of Merkel cell carcinoma patients: Detailed recurrence data and an integrated risk analysis approach
Merkel cell carcinoma is most likely to recur within two years of diagnosis, and factors like immune suppression, being over 75, and male sex increase this risk.
research Effects of Restraint Stress and Allopregnanolone Inhibition on Amphetamine Locomotor Sensitivity
Targeting neurosteroids may help prevent drug relapse.
research Glibenclamide reverses cromakalim-induced anti-ischemic effect in conscious rabbits
research Use of platelet rich plasma for skin rejuvenation
Platelet-rich plasma (PRP) is effective and safe for improving skin appearance.
research Can chronic recurrent dermatoses be managed through augmented virtual reality?
Augmented virtual reality can help manage chronic skin conditions.
research Enzalutamide/finasteride/goserelin/zoledronic-acid
research Treatment Strategies for Pediatric Trichotillomania: State‐of‐the‐Art Review on Progress and Persistent Challenges
Behavioral interventions, especially habit reversal training, are most effective for treating trichotillomania in children.
research Remote photobiomodulation ameliorates behavioral and neuropathological outcomes in a rat model of repeated closed head injury
Remote photobiomodulation improves brain injury outcomes and behavior in rats.
research “Prick or treat”: a case of systemic reaction during intradermal tests with beta-lactams
Longer treatment with vismodegib lowers relapse risk in basal cell carcinoma.
research 572 Defining chronic wound types in recessive dystrophic epidermolysis bullosa patients for clinical outcome assessment
The conclusion is that differentiating wound types in RDEB patients is important for clinical trials and understanding the disease.