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CAR-T cell therapy shows promise for treating autoimmune disorders but faces challenges like complex manufacturing and limited tissue penetration.

Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.

A mouse model for studying scleroderma in chronic graft-versus-host disease was successfully created.

Researchers created an efficient method to extract DNA from marmoset hair, avoiding blood chimerism.

Male-to-female skin grafts in mice are rejected due to sex-linked antigens.

Alopecia areata can be transferred through stem cell transplants from affected siblings.

Dual TCR Treg cells are common in various mouse tissues and show diverse characteristics.

Understanding cellular interactions in VCA may lead to better treatments and reduce rejection.

Dual TCR Treg cells are common in mouse tissues and vary by location.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Tortoiseshell tomcats with XX/XY chimerism can be fertile.

Engineered skin with hair follicles can improve burn treatments.

Engineered skin can grow chimeric hair follicles only with mouse dermal papilla cells.

Chronic graft-versus-host disease in the skin shows strong Th1 immune response and unique barrier issues.

γδ T cells adapt uniquely to different tissues in mice.

Using an anti-ICAM-1 antibody with rapamycin improves hair transplant survival in monkeys.

Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

scMC effectively separates biological signals from technical noise in single-cell genomics data.

Key genes can rewire networks, changing skin appendage types.

Combining UVB irradiation and anti-CD154 antibody improves hair follicle transplant survival.

Using regulatory T cells and Rapamycin together improves chronic graft-versus-host disease treatment outcomes in mice.

Nestin-expressing blood vessels help skin transplants survive and heal.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Non-myeloablative stem cell transplants are a promising, less toxic option for older or weaker patients, with fewer side effects and good outcomes.

Regulating keratinocyte growth in engineered skin can improve wound healing.

Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.

A specific genetic trait in tumor cells is linked to longer survival without disease in certain lymphoma patients.