86 citations
,
April 2016 in “Nature Communications” Notch1 helps skin heal by attracting specific immune cells.
35 citations
,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
82 citations
,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
120 citations
,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
82 citations
,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
11 citations
,
March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
10 citations
,
December 2015 in “Clinics in Dermatology” Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.
111 citations
,
January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
103 citations
,
March 2011 in “PLoS Biology” Birds can lose neck feathers due to a genetic change that increases a gene's activity, helping them adapt to heat.
86 citations
,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
59 citations
,
June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
2 citations
,
September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.
58 citations
,
June 2018 in “Scientific reports” Researchers found 15 new genetic links to skin traits in Japanese women.
31 citations
,
March 2013 in “Gene” Signaling pathways are crucial for hair growth in goats.
January 2025 in “Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
2 citations
,
August 2020 in “Scientific reports” Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
54 citations
,
July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
12 citations
,
April 2014 in “Facial Plastic Surgery Clinics of North America” Direct excision techniques can rejuvenate the neck but may not enhance the jawline and could cause neck-face disharmony if done incorrectly.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
41 citations
,
June 2003 in “Journal of The American Academy of Dermatology” Long-term minoxidil use can cause pseudoacromegaly, but stopping it improves symptoms.
17 citations
,
April 2006 in “Dermatologic Clinics” Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.
48 citations
,
October 2010 in “Archives of Dermatological Research” Juvéderm fillers effectively reduce wrinkles for up to 21 months with less filler needed for repeat treatments.
15 citations
,
September 2018 in “Medicine” Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.