37 citations
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January 2008 in “Gynecological Endocrinology” Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.
4 citations
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October 2006 in “Anais Brasileiros de Dermatologia” Contact dermatitis treatment for alopecia areata can lead to temporary hair loss.
7 citations
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September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
13 citations
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July 2008 in “Biomedical Chromatography” The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
1 citations
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January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
6 citations
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April 1989 in “The American Journal of the Medical Sciences” Glucocorticoids can cause long-term loss of body hair by lowering adrenal androgens.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
May 2017 in “Urology and andrology” Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
1 citations
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April 2013 in “The FASEB Journal” 3α‐OH‐DHP is essential for reducing nerve activity related to blood pressure control during pregnancy.
1 citations
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February 2022 in “Case reports in endocrinology” An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
15 citations
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June 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride doesn't affect erections much, but may decrease libido in men.
October 2025 in “Journal of the Endocrine Society” Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.
25 citations
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November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.
January 1993 in “Проблемы Эндокринологии” Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.
July 2024 in “Journal of Investigative Dermatology” 5-alpha reductase inhibitors don't increase breast cancer or benign breast disorder risk in women.
18 citations
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November 2012 in “Current opinion in urology” Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Anti-androgens help manage PCOS symptoms like excess hair and acne.
2 citations
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January 2005 in “PubMed” Women with excessive body hair often have higher male hormones and related health issues.
October 2024 in “Journal of the Endocrine Society” Gender-affirming hormone therapy affects metabolism differently based on treatment type.
121 citations
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November 2020 in “Endocrine” Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
44 citations
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January 1999 in “Advances in pharmacology” The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.
May 2025 in “IDOSR JOURNAL OF BIOLOGY CHEMISTRY AND PHARMACY” Dietary phytochemicals may help improve male hormonal health.
38 citations
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December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
2 citations
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March 2020 in “Baghdad Science Journal” Finasteride effectively reduces DHT and E2 levels, helping with prostate enlargement.
24 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
February 2026 in “Toxicology Letters” MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
3 citations
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October 2024 in “The Journal of Clinical Endocrinology & Metabolism” Potential androgen excess signs vary by demographics and health, needing inclusive evaluation.
87 citations
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May 2018 in “Scientific Reports” Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
April 2022 in “The Journal of Urology” Men may experience long-term sexual dysfunction after stopping Finasteride.