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research Apoptotic cells may drive cell death in hair follicles during their regression cycle
Apoptotic cells help cause hair follicle cell death during regression.
research 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling
Senescent fibroblasts can help start tumors in normal skin cells.
research Small RNAs Loom Large During Reprogramming
MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.
research 1446 RNase L acts as a regeneration suppressor
RNase L suppresses regeneration in mammals.
research Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy
Revertant cell therapy shows promise for treating type XVII collagen deficiency, but better cell selection methods are needed.
research Assessment of replication rates of human keratinocytes in engineered skin substitutes grafted to athymic mice
Regulating keratinocyte growth in engineered skin can improve wound healing.
research Hair Follicle Pluripotent Stem (hfPS) Cells
research Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Skin stem cells orchestrate de novo generation of extrathymic regulatory T cells to establish a temporary protective niche during wound healing
Skin stem cells help create protective immune cells during wound healing.
research Modeling of ionizing radiation induced hair follicle regenerative dynamics
Hair follicles can regenerate after radiation damage but not during a specific growth phase.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research The Hair Follicle Stem Cell as the Paradigm Multipotent Adult Stem Cell
Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.
research Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells
Hair follicle stem cells can become corneal-like cells, potentially helping restore vision.
research All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Growth Differentiation Factor 11 (GDF11)/Transforming Growth Factor - β (TGF - β)/Mesenchymal Stem Cells (MSCs) Balance: A Complicated Partnership in Skin Rejuvenation
MSCs help rejuvenate skin by promoting cell growth and reducing inflammation.
research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.
Activating telomerase can boost hair follicle stem cell growth and hair production.
research Stem Cells in Ophthalmology
research States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility
Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
research Current advances in stem cell-based therapies for hair regeneration
Stem cell therapies show promise for hair regrowth but face production and application challenges.
research Optogenetically Controlled TrkA Activity Improves the Regenerative Capacity of Hair‐Follicle‐Derived Stem Cells to Differentiate into Neurons and Glia
Blue-light activation of TrkA improves hair-follicle stem cells' ability to become neurons and glial cells.
research Epidermis reconstructed from the outer root sheath of human hair follicle on de-epidermized dermis. Effect of retinoic acid
research Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human‐Induced Pluripotent Stem Cells
Scientists developed a way to create skin and hair cells from human stem cells, which could help treat burns and restore hair.
research Oxidative Stress and Hormone-regulated Dermal Papilla Cell-targeted Nanomodulators: Reverse Cellular Senescence for Androgenetic Alopecia Therapy
Targeted nanomodulators can rejuvenate cells and promote hair growth in androgenetic alopecia.
research 1393 Lower proximal cup cells but not bulge stem cells regenerate hair follicles after chemotherapy injury
Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.
research HUMAN HAIR KERATIN PROTEIN, HAIR FIBERS AND HYDROXYAPATITE (HA) COMPOSITE SCAFFOLD FOR BONE TISSUE REGENERATION
research Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?
Cellular and immunotherapies show promise for healing chronic wounds but need more research.
research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.