10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
10 citations
,
October 2016 in “Experimental Dermatology” Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
9 citations
,
August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
9 citations
,
May 2022 in “Frontiers in Cellular Neuroscience” Mesenchymal stromal cell therapies show promise for treating various diseases but need more research and standardization.
4 citations
,
January 2024 in “The Scientific World JOURNAL” Understanding hair follicle development helps create treatments for hair loss and improve hair health.
2 citations
,
May 2018 in “Journal of Investigative Dermatology” Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.
April 2026 in “International Journal of Molecular Sciences” Diabetic patients need tailored cosmetic treatments for skin aging, with new therapies showing promise.
Fraser's Dolphin can heal skin wounds with minimal scarring, unlike humans.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
January 2025 in “Case Reports in Dermatological Medicine” Exosome therapy improved hair growth and quality in a child with hair issues.
February 2024 in “Frontiers in physiology” Hair follicle stem cells help skin heal and grow during stretching.
July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
April 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.
April 2018 in “Journal of Investigative Dermatology” Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
21 citations
,
June 2016 in “PloS one” Zebrafish need MYC and FGF to regenerate inner ear hair cells.
71 citations
,
January 2020 in “Stem Cells International” Epidermal stem cells help heal skin, but how they work is still unclear.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
January 2020 in “eScholarship (California Digital Library)” Signaling factors and gene-driven cell adhesion are crucial for wound healing and embryo development.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Double stranded RNA helps skin wounds heal by coordinating specific proteins and signaling pathways.
March 2017 in “Trichology and cosmetology:” Psoriasis treatment may affect body hair growth, with a complex relationship between skin and hair growth mechanisms.
April 2016 in “Journal of Investigative Dermatology” Mice without the p21 gene can fully regenerate injured ears due to reduced Sdf1 increase and leukocyte recruitment, suggesting new ways to induce tissue regeneration in mammals.
12 citations
,
January 2021 in “Cell Transplantation” Baby teeth stem cells can help grow hair in mice.
3 citations
,
October 2022 in “Frontiers in Cell and Developmental Biology” Understanding tissue regeneration requires new experiments and historical insights to improve nerve healing.
92 citations
,
March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
35 citations
,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
32 citations
,
December 2017 in “Stem Cells Translational Medicine” We need to understand more about regeneration to improve human tissue healing.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.