research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
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research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration
Polycomb Repressive Complex 2 is not needed for hair regeneration.
research Risk of rhabdomyolysis from 5-α reductase inhibitors
Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.
research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Recent therapeutic developments for acne
New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
research Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia
Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
research Expression of beta-catenin, p63 and CD34 in hair follicles during the course of androgenetic alopecia
Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.
research The role of CTHRC1 in hair follicle regenerative capacity restored by plantar dermis homogenate
CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.
research Five years after Keogh's review of regulation in the aesthetics sector, what has changed?
Some improvements in the aesthetics sector have been made, but patient protection is still lacking due to no compulsory register for practitioners and non-prescription dermal fillers.
research Scientific precision in titles of research papers published in three dermatology journals
Many research paper titles in dermatology journals lack scientific precision.
research Diversity of Adult Stem Cell Niches in the Dermal Compartment of Skin
The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
research Dusko Ilic† explores the latest developments in the field of stem cell research and regenerative medicine
Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.
research Investigating tralokinumab-related adverse events in treating atopic dermatitis: insights from the FAERS database
Tralokinumab for atopic dermatitis may cause eye issues and skin reactions, needing careful monitoring.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
research Enhancing the diagnostic yield of monogenic diabetes in unresolved cases with early-onset hyperglycemia
Combining genetic and physical data improves diagnosis and treatment for early-onset monogenic diabetes.
research Gut Microbiota and Autoimmune Alopecia Areata: Current Insights from the Literature
Gut microbiota changes might play a role in alopecia areata, and microbiome-targeted treatments show promise.
research Artificial intelligence in trichology - usage and prospects
AI can improve hair care but needs legal clarity and is not widely used in Poland yet.
research Reviewer #1 (Public review): Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation
Whiskers can form without sensory nerves or Foxd1, thanks to Meis2 in mesenchymal cells.
research Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation
Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
research Clinical-Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome (PCOS) Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment
Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.
research Cell death as an architect of adult skin stem cell niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Enhancing diagnostic yield of monogenic diabetes through phenotypic and molecular reanalysis of 128 individuals with young onset hyperglycemia: highlighting the significance of accurate case characterization
Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.
research Investigation of Insulin-Like Growth Factor 1 Receptor Expression in Cases of Sacrococcygeal Pilonidal Sinus
Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
research Hair cortisol as a biomarker for mood in bipolar disorder: a pilot study
Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.
research An Investigation Into the Frequency of Use of Traditional and Complementary Medicine in Patients Presenting to the Dermatology Clinic: A Survey Study
Some dermatology patients in Turkey use traditional medicine, with herbal remedies being most common, but these treatments can have mixed results and risks.
research Anogenital distance as a biomarker for incomplete masculinization : Molecular mechanisms in the perineum
A short male anogenital distance may indicate incomplete masculinization due to disrupted androgen action.
research Discussion of “A hybrid phase I‐II/III clinical trial design allowing dose re‐optimization in phase III” by Andrew G. Chapple and Peter F. Thall
The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
research Fertility and Sterility Vol 101 No 4, April 2014
The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
research Literature Reviews
Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.