47 citations
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December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
43 citations
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January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
40 citations
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August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
40 citations
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April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
38 citations
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December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
32 citations
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April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
31 citations
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April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
29 citations
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December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
27 citations
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April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
26 citations
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June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
26 citations
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October 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
25 citations
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March 2012 in “Journal of Dermatological Science” Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
23 citations
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December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
22 citations
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June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
19 citations
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August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
19 citations
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October 2011 in “Clinics in Dermatology” New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
16 citations
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January 2021 in “Dermatology and therapy” An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
13 citations
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May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
11 citations
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February 2021 in “Biomedicines” Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.
11 citations
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August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
11 citations
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April 2020 in “Life sciences” Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
10 citations
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November 2019 in “Cold Spring Harbor Perspectives in Biology” Stem cells are more dynamic and adaptable than previously believed.
9 citations
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August 2024 in “Tissue Engineering and Regenerative Medicine” Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
9 citations
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March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
8 citations
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February 2022 in “Journal of Clinical Medicine Research” The MATH+ protocol aims to improve COVID-19 outcomes using a combination of specific treatments.
7 citations
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September 2021 in “Dermatology and Therapy” Vaccination is crucial for psoriasis patients on immunosuppressive therapy to manage COVID-19 risks.
4 citations
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January 2022 in “Journal of clinical and translational research” Chitosan-based dressings reduce inflammation and speed up skin wound healing.
4 citations
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May 2021 in “Lasers in Surgery and Medicine” Light therapy reduces scalp inflammation, boosts hair regrowth with Minoxidil 2%.
2 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
1 citations
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October 2025 in “Cureus” Ritlecitinib may cause severe musculoskeletal pain in some alopecia universalis patients.