research 5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction
5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
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research Pramipexole
Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
research Androgens and Antiandrogens
Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
research A10.09 Safety data of four treatment regimens in early rheumatoid arthritis patients
All four treatments for early rheumatoid arthritis had similar and mostly mild side effects.
research 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine
A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
research Bupropion for the treatment of fluoxetine non-responsive trichotillomania: a case report
Bupropion may help treat trichotillomania when fluoxetine doesn't work.
research The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression
5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.
research Clinical and metabolic effects of medroxyprogesterone acetate and ethinyl estradiol plus drospirenone in women with polycystic ovary syndrome
MPA improved hormonal imbalances and acne in women with PCOS without affecting metabolism.
research Increased risk of telogen effluvium with tirzepatide compared to other weight-loss medications: a retrospective cohort TriNetX database study
research Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Finasteride Tablets
research Testosterone replacement in the setting of Finasteride therapy: a therapeutic dilemma
research Finasteride Tablets
research Table_1_Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea.xlsx
Melatonin may treat rosacea and Alzheimer's by reducing inflammation and affecting blood vessel growth.
research Improvement in Patient‐Reported Emotional Symptoms and Activity Limitations due to Hair Loss in Patients With Alopecia Areata Treated With Ritlecitinib: Additional Analyses From ALLEGRO ‐2b/3
Ritlecitinib improves emotional well-being and activity levels in alopecia areata patients.
research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error
research Finasteride-related self-harm and suicidal ideation
research Signal Detection of Depression and Suicidality Associated with Finasteride and Dutasteride: Updated Pharmacovigilance Evidence and Recommendations for Comprehensive Psychiatric Assessment
Finasteride may cause depression and suicidal thoughts, especially in young men.
research Faculty Opinions recommendation of Persistent sexual dysfunction and depression in finasteride users for male pattern hair loss: a serious concern or red herring?
Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
research The interaction between finasteride and corticosterone levels: implications for depression-, and anxiety-like behavior and hippocampal synaptic plasticity in male rats
Chronic finasteride use in male rats doesn't strongly cause depression or anxiety due to adaptive stress hormone changes.
research Solubilization and Solid‐State Characterization of a Poorly Soluble 5‐α Reductase Inhibitor
GI197111X is best dissolved in Capmul MCM for trials.
research Drug News
Actemra is approved for a specific artery condition, HIV treatment adherence has improved, women may pay more for a hair loss product, and incorrect dosing of blood thinners can be risky.
research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men.
Finasteride doesn't affect erections much, but may decrease libido in men.
research Multidimensional assessment of adverse events of finasteride：a real-world pharmacovigilance analysis based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024
Finasteride can cause long-term side effects like sexual dysfunction and depression.
research The Safety and Efficacy of a Novel Saw Palmetto ( Serenoa repens ) Extract for Promoting Hair Growth in Adults With Self‐Perceived Thinning Hair: 180‐Day Results
SEREVELLE safely and effectively promotes hair growth in adults with thinning hair.
research Seizure control and side-effect profile after switching adult epileptic patients from standard to extended-release divalproex sodium
Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.
research Alpha-blockers/finasteride: no benefit in ED
research Double Dosing
Taking the same medication under different brand names caused harmful side effects.
research Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review
5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.
research Retinoids - new uses and new synthetic agents
New retinoids are effective for various skin conditions and are being developed to have fewer side effects.