research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
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270-300 / 1000+ results research Intercellular Adhesion Molecule-1 and Hair Follicle Regression
ICAM-1 helps regulate hair growth cycles and skin remodeling.
research Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions
LONRF1 is important for oxidative damage response and tissue remodeling during wound healing.
research 1391 Cell death functions in hair follicle regeneration
Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.
research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
research 573 Biomarkers quantifying changes in the hair follicular extracellular matrix are elevated in patients with alopecia
Changes in hair follicle structure may help diagnose and monitor alopecia.
research Thymosin β4 promote the wound healing of cornea
Thymosin β4 helps heal corneal wounds.
research BAF200 Is Required for Heart Morphogenesis and Coronary Artery Development
BAF200 is essential for proper heart and coronary artery formation.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research 有效成分으로 접근해본 두피노화방지(Scalp Anti-Ageing)와 탈모방지(Anti-Hair loss)
GHK-Cu and propolis may help prevent scalp aging and hair loss.
research Wound healing: cellular mechanisms and pathological outcomes
Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
research Transforming growth factor-β in stem cells and tissue homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research An mTurq2-Col4a1 mouse model allows for live visualization of mammalian basement membrane development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research OBESITY-RELATED FACTORS INVOLVED IN ENDOPLASMIC RETICULUM STRESS INDUCTION IN ADIPOCYTES
Adipose tissue changes in obesity can trigger stress in fat cells.
research My Experiences in Using Autologous Human Hair Follicular Stem Cells (AMT) With Regenera Technology Combination With Platelet Rich Plasma (PRP) for Androgenetic Alopecia Treatments – in Both Male Pattern Hair Loss (MPHL)&Female Pattern Hair Loss (FPHL) in Asian Populations.
The combination of hair follicle stem cells and PRP shows promise for treating hair loss in Asian men and women.
research Costunolide—A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.
research The role of R-spondins and their receptors in bone metabolism
R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
research The Physician's Guide to Platelet-Rich Plasma in Dermatologic Surgery Part II: Clinical Evidence
Platelet-rich plasma is most effective for hair loss treatment and wound healing in skin surgery, but more research is needed for consistent results.
research Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation
Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.
research Vibration, a treatment for migraine, linked to calpain driven changes in actin cytoskeleton
Vibration treatment may reduce migraine pain by changing cell structures.
research Beyond wound closure: translational opportunities and barriers of mesenchymal stem cells and their extracellular vesicles in burn management
This review discusses the potential of mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) as a cell-free therapy for burn management, focusing on their roles in inflammation regulation, angiogenesis, epithelial regeneration, and ECM remodeling. The authors propose a framework for translating these therapies into clinical practice, highlighting their advantages in addressing inflammation, regeneration, and fibrosis. However, challenges such as donor consistency, GMP compliance, standardization of quality attributes, and optimization of administration strategies need to be addressed. The review emphasizes the importance of establishing standardized production and quality-control systems and conducting multicenter randomized studies to facilitate the translation of MSC/EV therapies from research to clinical application.
research Uncovering Novel Landscape and Functional MicroRNA‐Targets for Androgenetic Alopecia
This study investigates the role of microRNAs (miRNAs) in androgenetic alopecia (AGA) by integrating miRNA data with existing mRNA sequencing profiles to construct miRNA-mRNA regulatory networks. The research highlights the downregulation of predicted target genes related to structure modulation, suggesting that microenvironment remodeling may contribute to hair follicle stem cell dysfunction in AGA. An AGA model using organ-cultured balding hair follicles was established to explore miRNA roles, revealing that miR-146b-5p could promote hair growth and improve the inflammatory microenvironment in AGA hair follicles. This miRNA presents a promising target for AGA treatment.
research Glucose-Activated Nanoreactor Initiating Cascade Reaction to Remodel Immune Microenvironment for Promoting Diabetic Wound Healing
MCP@G improves diabetic wound healing by reducing stress and promoting tissue repair.
research Lactiplantibacillus plantarum ZJUIDS51 improves androgenic alopecia via gut-skin axis
Lactiplantibacillus plantarum ZJUIDS51 can help regrow hair and improve scalp health in androgenic alopecia.
research Comprehensive analysis of differences in cashmere production performance in Liaoning cashmere goats by using metabolomics and transcriptomics
Liaoning cashmere goats grow more cashmere by boosting fat production, supporting hair structure, and controlling inflammation.
research Biologically Driven Innovations in Aesthetic Surgery: Advances in Regenerative and Cellular Therapies
Regenerative therapies are improving aesthetic surgery by enhancing tissue quality and healing.
research Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update
Exosomes may help with hair growth and scar healing, but more research is needed.
research Research Progress on Fractional CO2 Laser in Multimodal Therapy
Fractional CO2 laser therapy effectively improves skin conditions and recovery when combined with other treatments.
research Dynamic Hyaluronic Acid Hydrogels for Comprehensively Regulating Inflammation, Angiogenesis, and Metabolism to Effectively Proheal Diabetic Wounds
The new hydrogel helps heal diabetic wounds by reducing inflammation and improving tissue repair.
research Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle
Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.