research Einfluss des Lipidmusters und der Morphologie der Epidermis auf transdermale Permeationsraten im In-vitro-Versuch
Porcine skin is a good substitute for human skin in drug diffusion tests.
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research Bayesian measurement-error-driven hidden Markov regression model for calibrating the effect of covariates on multistate outcomes: Application to androgenetic alopecia
Model improves accuracy in predicting hair loss effects.
research Bioequivalent Assessment of Finasteride Granules in Chinese Healthy Volunteers
Finasteride granules and tablets work the same in the body.
research Clinical Considerations of Bioequivalence for Topical Dermatologic Drugs
Current methods for assessing bioequivalence of topical drugs are limited and lack standardization.
research A hair growth questionnaire for use in the evaluation of therapeutic effects in men
The questionnaire effectively measures men's perceived hair growth and can distinguish between different treatments and dosages.
research Evaluation method of the degree of hair damage. (I). Measurement of tensile strength of human hair by "the multi-point tension test method".
The method accurately measures hair damage and strength, revealing effects of cosmetics and metal correlations.
research 652 Short cell cycle duration is a phenotype of human epidermal stem cells
research A concise review- Development of an analytical method and validation of dutasteride
New methods for measuring dutasteride are effective and reliable.
research New spectrophotometric methods for the determination of Minoxidil
New, simple, and cost-effective methods can accurately measure Minoxidil in medicines.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Reporting Quality of Drug Safety Systematic Reviews: A Cross-Sectional Study
Cochrane and non-Cochrane drug safety reviews report well in PRISMA but poorly in PRISMA harms, with non-Cochrane needing improvement.
research 689 Cell-type-specific nascent transcriptomics through PRECISE-seq reveal molecular principles of tissue dynamics
research Drug repositioning: current approaches and their implications in the precision medicine era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects
Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.
research Recurrent Pilo-Nidal Sinus: Secret Of Recurrence
Thorough cleaning and hair removal are essential to effectively treat and prevent recurrent pilonidal sinus.
research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry
New methods can detect finasteride's major urinary metabolite in urine for up to 49 hours.
research Identification of Ovine KRTAP28-1 and Its Association with Wool Fibre Diameter
KRTAP28-1 gene can help breed sheep with finer wool.
research Therapeutic maintenance effect of finasteride 1 mg every other month regimen in androgenetic alopecia and study on the difference in response to finasteride treatment: A prospective cohort study
Taking finasteride every other month can still help with hair loss but may be less effective over time compared to taking it daily.
research Expression of keratins K6 and K16 in regenerating mouse epidermis is less restricted by cell replication than the expression of K1 and K10.
Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
research Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research The Cross-section Trichometer: A New Device for Measuring Hair Quantity, Hair Loss, and Hair Growth
The Cross-section Trichometer is a new tool that can measure hair quantity and detect hair loss and growth.
research A Simple Technique for Revealing the Surface Pattern of Hair
A simple method can show hair's surface pattern.
research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat
Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
research Follow-Up of 1 mg Finasteride Treatment of Male Pattern Baldness-Difference between Clinical Trials and Private Office Follow-Up: Influences on Prescribing Habits Evaluated
Finasteride showed limited hair growth and low patient compliance in treating male pattern baldness.
research Advanced chemical imaging and comparison of human and porcine hair follicles for drug delivery by confocal Raman microscopy
Confocal Raman microscopy can effectively study drug delivery in hair follicles using pig ear models.
research Validation of scalp coverage scoring methods for scalp hair loss in male pattern hair loss (androgenetic alopecia)
Scalp coverage scoring accurately measures hair loss and treatment effectiveness.
research Molecular and Cellular Characterization of Avian Reticulate Scales Implies the Evo–Devo Novelty of Skin Appendages in Foot Sole
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research What should it take to describe a substance or product as 'sperm-safe'
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Corrigendum
The 7.1% withdrawal rate was in the oral finasteride group, not the topical one.