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The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Metformin may improve acanthosis nigricans by reducing insulin resistance.

Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Vitamin D receptor and hairless protein are essential for hair growth.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Hairless protein helps control hair growth by regulating vitamin D receptor activity.

The vitamin D receptor can work without its usual activating molecule.

PPAR alpha may help in hair growth and could be a target for treatment.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Vitamin D receptor and mediator 1 are crucial for healthy skin and hair growth.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.

Hairless protein can block vitamin D activation in skin cells.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Vitamin D receptor is crucial for hair health and may help treat hair loss.

Vitamin D Receptor is crucial for normal skin and hair growth.

μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.

Retinoids may improve hair growth in androgenic alopecia when used with other treatments.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

The right amount of retinoic acid is essential for normal hair growth and development.