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Mutations in the P2RY5 gene cause hereditary woolly hair.

Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.

Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.

Different treatments for skin conditions were found to be effective and generally safe, with biologics recommended as the first choice for generalized pustular psoriasis.

Generalized glucocorticoid resistance causes hormone imbalances and varied symptoms due to gene mutations.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.

New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.

Researchers created a mouse model of a type of rickets that does not cause hair loss.