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A new gene mutation causes vitamin D resistance and hair loss in two unrelated girls.

Patients with this syndrome can have different responses and worsening resistance to treatment over time.

5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The vitamin D receptor can affect gene activity even without its usual hormone in hair and skin.

Oral Acitretin effectively resolved symptoms in a child with Netherton syndrome.

Vitamin D and its receptor help regulate skin functions like cell growth, immunity, and hair cycle.

A rare genetic mutation causes resistance to vitamin D, leading to severe rickets and requires high doses of calcium and vitamin D for management.

Retinoic acid reduces cell damage from oxidative stress.

Vitamin D receptor helps prevent skin tumors.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Oral retinoids may help some patients with hard-to-treat lichen planopilaris, but more research is needed.

Rhododendrol in skin-whitening products can cause skin depigmentation and immune reactions.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Systemic retinoids may effectively treat erosive pustular dermatosis of the scalp.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Type 2 5α-reductase plays a key role in hair loss.

Female rats aged 8 weeks are best for this model.

Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

The document discusses various skin disorders and new therapeutic approaches.

Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The vitamin D receptor can regulate genes and affect hair and hormone levels without its usual activator.

A mutation in the vitamin D receptor causes severe resistance to vitamin D, affecting bone health but not hair growth.

Topical retinoids are important for treating acne effectively and safely.