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Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro

58 citations , June 1987 in “Archives of Dermatological Research”

EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

research Epidermal growth factor and fibroblast growth factor accelerate proliferation of human hair bulb papilla cells and root sheath tibroblasts cultured in vitro

9 citations , March 1987 in “British Journal of Dermatology”

EGF and FGF can boost hair growth by speeding up cell growth.

research A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells

2 citations , January 1989

Researchers developed a method to grow skin-like tissue from hair cells.

research FORMATION OF A REGULAR NEO-EPIDERMIS BY CULTURED HUMAN OUTER ROOT SHEATH CELLS GRAFTED ON NUDE MICE

14 citations , April 1995 in “Transplantation”

Human hair follicle cells can be used to help heal and replace skin.

research Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells

31 citations , December 1991 in “Annals of the New York Academy of Sciences”

ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.

research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling

43 citations , January 2016 in “Cellular physiology and biochemistry”

Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.

research Role of the Differentiation of Root Epidermal Cells in Nod Factor (from Rhizobium meliloti)-Induced Root-Hair Depolarization of Medicago sativa

83 citations , March 1995 in “PLANT PHYSIOLOGY”

The differentiation stage of root epidermal cells is crucial for root hair depolarization in Medicago sativa when exposed to specific Nod factors.

Genome Wide Association Analysis of Root Hair Traits in Rice Reveals Novel Genomic Regions Controlling Epidermal Cell Differentiation

research Genome wide association analysis of root hair traits in rice reveals novel genomic regions controlling epidermal cell differentiation

2 citations , January 2023 in “BMC plant biology”

Scientists found new genetic areas that affect how rice root hairs grow and develop.

research Successful Treatment of Chronic Leg Ulcers with Epidermal Equivalents Generated from Cultured Autologous Outer Root Sheath Cells

99 citations , July 1996 in “Journal of Investigative Dermatology”

The study discussed the successful treatment of chronic leg ulcers using epidermal equivalents generated from cultured autologous outer root sheath cells. This approach involved cultivating cells from the patient's own hair follicles to create skin grafts that were then applied to the ulcerated areas. The results indicated that this method was effective in promoting healing in chronic leg ulcers, suggesting a promising therapeutic avenue for patients with such conditions. The study highlighted the potential of using hair follicle-derived cells in regenerative medicine, particularly for skin repair.

research Differential Auxin-Transporting Activities of PIN-FORMED Proteins in Arabidopsis Root Hair Cells

122 citations , May 2010 in “Plant Physiology”

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein

51 citations , February 2004 in “Journal of Investigative Dermatology”

MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.

research Organotypic culture of outer root sheath cells from human hair follicles using a new culture device

35 citations , August 1987 in “In Vitro Cellular & Developmental Biology - Plant”

The new device improves human hair follicle cell growth and differentiation.

research Epidermal keratinocyte stem cells: their maintenance and regulation

25 citations , December 1992 in “Seminars in cell biology”

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

research Isolation of Multipotent Nestin-Expressing Stem Cells Derived from the Epidermis of Elderly Humans and TAT-VHL Peptide-Mediated Neuronal Differentiation of These Cells

12 citations , May 2013 in “International Journal of Molecular Sciences”

Stem cells from elderly skin can become neurons, offering potential for brain therapy.

research Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research Barley disease susceptibility factor RACB acts in epidermal cell polarity and positioning of the nucleus

41 citations , April 2016 in “Journal of experimental botany”

RACB in barley is crucial for cell polarity and nucleus positioning, aiding fungal infection.

research Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel

4 citations , July 2022 in “Annals of translational medicine”

Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.

research Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro

135 citations , November 1987 in “Differentiation”

Outer root sheath cells consistently express certain keratins influenced by their environment.

research VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway

23 citations , June 2012 in “Molecular Biology Reports”

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

research Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel

7 citations , July 2016 in “Journal of Biomedical Materials Research Part A”

cGEL hydrogel improves melanin production in skin cells, making it a promising option for skin treatments.

CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin

research CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin

8 citations , August 2016 in “Journal of pathology and translational medicine”

CD99 is highly present in certain skin cells and could help treat skin conditions.

research Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle.

44 citations , August 1990 in “PubMed”

Keratins K1 and K10 are found in the inner root sheath and cuticle of human hair follicles.

research Arabinogalactan proteins are involved in root hair development in barley

32 citations , December 2014 in “Journal of experimental botany”

Certain proteins are essential for the growth of root hairs in barley.

research Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.

198 citations , November 1989 in “The Journal of Cell Biology”

Keratin K14 expression varies between hair follicles and epidermis, affecting cell differentiation.

research Inductive Properties of Hair Follicle Cells

68 citations , December 1991 in “Annals of the New York Academy of Sciences”

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.

BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions

research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions

50 citations , September 2014 in “Stem cell reports”

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.