5 citations
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February 2024 in “Clinical Pharmacokinetics” A 50 mg daily dose of ritlecitinib is effective for alopecia areata, with temporary treatment breaks up to 6 weeks not affecting results.
May 2025 in “Birth Defects Research” YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.
13 citations
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January 2021 in “The American journal of gastroenterology” Sirolimus effectively reduces lesions and improves quality of life in Blue Rubber Bleb Nevus Syndrome with manageable side effects.
September 2022 in “Zenodo (CERN European Organization for Nuclear Research)”
49 citations
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December 2017 in “Journal of pharmaceutical and biomedical analysis” The method effectively detects banned substances in urine for sports antidoping.
17 citations
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August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.
3 citations
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December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal” Compound 3 protects the heart from damage by activating A1-adenosine receptors.
22 citations
,
November 2002 in “Clinical journal of oncology nursing” Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.
198 citations
,
September 2007 in “Clinics in Dermatology” Radiofrequency devices effectively tighten skin without surgery.
3 citations
,
June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
7 citations
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March 2025 in “Free Radical Biology and Medicine” Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
2 citations
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January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
August 2024 in “Latin American Journal of Development” 5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
January 2025 in “Analytical Methods” A new fluorescent material can detect dextran sulfate sodium, turning green when present, useful for forensic and environmental monitoring.
16 citations
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February 2009 in “Clinical neurology and neurosurgery” Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.
16 citations
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May 1995 in “Biochemical and Biophysical Research Communications” Both enzyme forms can sulfate minoxidil.
5 citations
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May 2018 in “Drug Safety” Using electronic health records can help identify drug side effects but has some limitations.
18 citations
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August 2015 in “Biochemical and Biophysical Research Communications” XEDAR triggers a specific signaling pathway in cells.
25 citations
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October 2022 in “Ophthalmic Research” Red light therapy temporarily increased blood flow in the eye but didn't change other eye structures.
March 2010 in “The Journal of Urology” Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.
1 citations
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November 2008 in “Acta crystallographica” Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
18 citations
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October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics” The drug was successfully released into hair follicles using nanocarriers.
December 2023 in “Biological & pharmaceutical bulletin” IPM enhances skin penetration of hydrophilic drugs.
CCC1 is essential for ion balance and proper plant cell function.
25 citations
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September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
5 citations
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December 2016 in “International journal of biometeorology” Bright light during the day doesn't change most human clock genes but may slightly increase Rev-erb-ß.
December 2024 in “Journal of Biophotonics” Dual wavelength LEDs may help reduce hair loss by lowering DHT levels.