research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.
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research In Vitroandin VivoStructure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research The Efficacy and Safety of Making Rat Hypothyroidism Model through Intramuscular Injection of 131Iodine
Intramuscular injection of 131I is a safe and effective way to induce hypothyroidism in rats without harming muscle tissue.
research Boron deficiency responses in maize (Zea mays L.) roots
Boron deficiency in maize affects leaf boron levels and nutrient uptake differently depending on root hair presence and soil type.
research Effects of High-dose Radioactive Iodine Therapy on Hormonal Profiles and Sperm Quality in Thyroidectomy Patients
High-dose radioactive iodine therapy does not harm fertility in thyroidectomy patients.
research Effects on swine of unilateral neutron irradiation, calcium, and zinc.
Radiation reduced zinc levels, growth, organ weights, and hair pigment in swine.
research SRXRF elemental mapping and source analysis of Pb,Fe,Cu and Zn in human hair from an inhabitant in a lead-zinc mining area
Lead levels in hair increased due to environmental exposure, while iron, copper, and zinc levels stayed stable.
research Bexxar, iodine I 131 tositumomab, Effective in Long Term Follow-up of Non-Hodgkin's Lymphoma
Bexxar is highly effective as a first treatment for non-Hodgkin's lymphoma, with most patients alive and many in remission after eight years.
research New fluorogenic probes for neutral and alkaline ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research Effects of Heavy Ions on Rabbit Tissues: Damage to the Forebrain
Heavy ions cause significant damage to rabbit forebrains, similar to other radiation effects.
research Hair radioactivity as a measure of exposure to radioisotopes
Hair can measure exposure to radioisotopes.
research Pattern of short-term adverse effects in patients undergoing low-dose radioactive iodine therapy
Short-term side effects of low-dose radioactive iodine therapy are common but temporary.
research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.
RUM-loaded SLN shows promise for treating acne and hair loss topically.
research Raman investigation of in vivo radiation exposure on melanin in murine hair
Raman spectroscopy can detect radiation exposure in mouse hair with high accuracy for up to 7 days.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research A Novel Ion – selective Polymeric Membrane Sensor for Determining Thallium(I) With High Selectivity
The sensor accurately measures thallium ions in solutions with high selectivity.
research Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Tellurium, Selenium, Antimony and Arsenic in Scalp Hair
research Decision letter: The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome
ANE syndrome is caused by a mutation in the RBM28 protein that disrupts ribosome assembly.
research Ruby laser treatment for hirsutism: clinical response and patient tolerance
Ruby laser treatment is effective and well-tolerated for reducing hair growth.
research A new mutation Rim3 resembling Re den is mapped close to retinoic acid receptor alpha (Rara) gene on mouse Chromosome 11
research Bicalutamide
research Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling
Strontium zinc silicate may help treat osteoporosis and muscle loss.
research Evaluation of permissible level of soluble I-131 containing fission products for design of protective measures in livestock industry
Cows can safely graze after a nuclear incident if iodine exposure is managed, as doses below 30 Gy don't harm them long-term.
research Voltammetric detection with a comprehensive electrochemistry study of minoxidil using nuclear magnetic resonance and infrared analyses: Applications in the forensic and pharmaceutical fields
A new, quick method accurately detects minoxidil in drugs and cosmetics.
research An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma
The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.
research Subcellular localization of the five members of the human steroid 5α-reductase family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research The Development of BL 7660 as an Anti‐Acne Agent
BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.
research Root and root hair growth of oats: replaceability of calcium
Calcium is essential for normal root and root hair growth in oats.