May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
January 2025 in “Multimedialen Archiv und Publikationsserver der Christian-Albrechts-Universität zu Kiel (Christian-Albrechts-Universität zu Kiel)” Oxidized LDL reduces cell growth but affects stem cell differentiation less negatively than cytokine-induced inflammation.
12 citations
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September 2021 in “The International Journal of Developmental Biology” Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
124 citations
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October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
116 citations
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September 2020 in “Nature Communications” The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
65 citations
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March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
60 citations
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March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
57 citations
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June 2018 in “Nutrients” Celiac disease can cause skin problems that may get better with a gluten-free diet.
42 citations
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July 2015 in “Cosmetics” Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
32 citations
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November 2016 in “Journal of Dental Research” Pannexin 3 is important for bone formation and the development of bone cells.
29 citations
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September 2020 in “International Journal of Molecular Sciences” The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
29 citations
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December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
27 citations
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July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
20 citations
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June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
20 citations
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July 2020 in “Expert Opinion on Biological Therapy” Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
19 citations
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December 2016 in “PLOS ONE” Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
18 citations
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September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
17 citations
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April 2017 in “PLoS ONE” Hair follicle cells can become bone-like cells, useful for bone repair.
15 citations
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February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
12 citations
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February 2013 in “The Open Stem Cell Journal” DPSCs and SHED have great potential for medical treatments and tissue repair.
11 citations
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August 2019 in “Journal of Molecular Histology” NFIC helps rat dental cells grow and turn into bone-like cells.
11 citations
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May 2018 in “Philosophical Transactions of the Royal Society B” New materials help control stem cell growth and specialization for medical applications.
8 citations
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June 2024 in “APOPTOSIS” Caspases affect many cell functions and could help treat various diseases.
6 citations
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May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
4 citations
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May 2025 in “npj Parkinson s Disease” PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.