research Acute Selenium Toxicity Associated With a Dietary Supplement
A manufacturing error in a dietary supplement caused severe selenium poisoning, affecting many people and highlighting the need for stricter quality control.
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90-120 / 1000+ resultsresearch Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics
PCOS is influenced by various factors and may be managed by restoring gut health and using new therapies.
research New aspects of vitamin D metabolism and action — addressing the skin as source and target
research Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity
research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications
Nanocarriers can improve drug delivery through the skin by overcoming barriers.
research Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Wound Healing and Skin Regeneration
Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ<sup>5sup>-Δ<sup>4sup>-lsomerase in Human Adrenals and Gonads
Human adrenals and gonads have a unique enzyme for steroid hormone production.
research Pathological sequelae of long-haul COVID
Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
research The immunology of the porcine skin and its value as a model for human skin
Porcine skin is very similar to human skin, making it a useful model for research.
research Nestin expression in hair follicle sheath progenitor cells
Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
research The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research The complex relationship between TFEBscp> transcription factor phosphorylation and subcellular localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles
Human hair follicles can provide stem cells for regenerative medicine.
research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1
The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals
The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research The Rotterdam Study: 2016 objectives and design update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution
Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.
research SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells
SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.