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Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.

Androgens like testosterone make Staphylococcus aureus skin infections more common in men.

Men are more affected by COVID-19 due to differences in immune responses and protein expression.

Supplemental testosterone may lower liver cancer risk in hepatitis C patients.

Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.

Higher substance P levels may cause discomfort in hair loss patients.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Young and adult hamsters both respond similarly to testosterone and finasteride treatments, but young hamsters aren't good for testing the inhibitory activity of a specific enzyme.

Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Finasteride is safe and effective for hair loss in transgender men, but may affect testosterone therapy.

Liposomes are not better than acetone for applying DHT on skin.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Finasteride use may be linked to rare testicular tumor, but more research needed.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

The method detected sex hormones in some health supplements, with one containing banned testosterone.

These ovarian conditions cause high testosterone levels.

Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.

MK-386 lowers DHT in blood and skin but not in semen.