April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
February 2026 in “Biophysical Journal” 91 citations
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July 2004 in “Journal of Biological Chemistry” Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
March 2026 in “Folia Histochemica et Cytobiologica” LTBP1 is a key regulator in diseases and a potential target for new treatments.
3 citations
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April 2022 in “Research Square (Research Square)” PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.
The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.
12 citations
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August 2022 in “Stem cell reviews and reports” Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
December 2021 in “Figshare” BBS7 is crucial for maintaining periodontal health by supporting Shh signaling.
60 citations
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October 2020 in “Nature Communications” AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
December 2021 in “Figshare” BBS7 is crucial for maintaining healthy gums by regulating important signaling pathways.
324 citations
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May 2002 in “Oncogene” July 2026 in “Pediatric Allergy and Immunology” 54 citations
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February 2002 in “Carcinogenesis” Increasing SSAT makes skin more prone to cancer.
67 citations
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December 2013 in “Journal of Biological Chemistry” SCD1 is crucial for skin health and overall energy balance.
147 citations
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August 2005 in “The Plant Cell” The TIP1 gene is crucial for normal plant cell growth in Arabidopsis.
December 2021 in “Figshare” BBS7 is essential for maintaining healthy gums and teeth.
December 2021 in “Figshare” BBS7 is essential for healthy gums by supporting cell function and blood flow.
21 citations
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January 2018 in “Anticancer Research” NBCCS and BFHS might be the same syndrome, helping better identify and manage cases.
February 2026 in “Oncology Reviews” Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
December 2021 in “Figshare” BBS7 is essential for healthy gums and teeth by supporting cell function and blood flow.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” BBS7 is crucial for maintaining healthy periodontal ligaments by supporting Shh signaling.
50 citations
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September 2023 in “Biomarker Research” S100A6 is important for cell functions and can help diagnose and treat diseases.
January 2024 in “Wiadomości Lekarskie” The ABI1 gene contributes to prostate cancer progression and treatment resistance.
451 citations
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March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
December 2021 in “Figshare” BBS7 is essential for healthy gums by supporting cell function and blood flow.
January 2016 in “Zurich Open Repository and Archive (University of Zurich)” Dietary L-serine supplementation can reduce symptoms of HSAN1 by lowering harmful 1-deoxySL levels.
5 citations
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July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
62 citations
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March 2017 in “Journal of Investigative Dermatology” Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.
10 citations
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January 2020 in “Genes & Diseases” Circ-Smad5 slows cell growth by blocking a specific cell signaling pathway.