June 2023 in “Value in Health” This targeted review analyzed adverse events (AEs) in clinical studies of alopecia areata (AA) treatments, including 16 studies on 4 topical and 12 systemic therapies. The most frequently reported AEs were headaches (213 cases), nasopharyngitis (189), upper respiratory tract infections (188), acne (151), and folliculitis (49). Systemic treatments were mainly associated with headaches, URTIs, and nasopharyngitis, while topical treatments were linked to headaches, nasopharyngitis, and pruritus. The findings emphasize the need for therapies with better safety profiles and the importance of large-scale, double-blind, placebo-controlled trials to confirm the efficacy and safety of AA treatments.
July 2025 in “Biotechnology and Bioprocess Engineering” Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
February 2025 in “Journal of Cosmetic Dermatology” Patch testing is crucial to reduce allergic reactions in hair loss treatments.
January 2015 in “Hair therapy & transplantation” Some botanical products may help increase hair growth in people with alopecia, but more research is needed.
43 citations
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July 1984 in “Clinical and Experimental Dermatology” Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
34 citations
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July 2010 in “Expert Opinion on Drug Delivery” The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
24 citations
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June 2016 in “Acta dermato-venereologica” Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.
11 citations
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June 2018 in “Annales de dermatologie et de vénéréologie” Hair care products can cause skin irritation and allergies.
5 citations
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April 2023 in “Life” CCCA affects adolescents too, with genetic and environmental links, requiring careful diagnosis.
5 citations
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February 2022 in “Acta Biomaterialia” Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.