13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
44 citations
,
June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
5 citations
,
December 2018 in “Annals of plastic surgery” Some burn patients grew extra hair in areas treated with pressure garments or silicone.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
April 2022 in “The Egyptian Journal of Hospital Medicine” Platelet Rich Fibrin improves healing and reduces acne scars by slowly releasing growth factors.
1 citations
,
March 2023 in “Pharmaceutics” PBMCsec can help reduce and improve thick skin scars.
51 citations
,
January 2006 in “Wound Repair and Regeneration” MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
178 citations
,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” Targeting specific cell interactions may help treat skin fibrosis.
65 citations
,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
48 citations
,
March 2019 in “Frontiers in Physiology” Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
6 citations
,
July 2017 in “Clinics in Plastic Surgery” The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
1 citations
,
October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
February 2026 in “Preprints.org” New therapies and personalized approaches improve wound healing and patient quality of life.
February 2026 in “Exploration” Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
November 2021 in “International Journal for Research in Applied Science and Engineering Technology” Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.
July 2007 in “Clinical Risk” A woman got severe scalp burns from a salon's improper hair bleaching treatment.
78 citations
,
June 2021 in “Dermatology and Therapy” Future acne treatments should aggressively target inflammation to prevent scarring.
9 citations
,
November 2008 in “Facial Plastic Surgery” Effective scalp reconstruction requires a wide range of surgical skills and an understanding of hair biology.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
150 citations
,
June 2014 in “Biomaterials” Peptide hydrogels heal burn wounds faster and better than standard dressings.
25 citations
,
June 2013 in “Obesity Reviews” Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.
18 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Lasers, microneedling, and PRP improve skin rejuvenation and repair, with PRP enhancing the effects when combined with other treatments.
32 citations
,
December 2015 in “PloS one” P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
74 citations
,
August 2023 in “Frontiers in Immunology” Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.
48 citations
,
May 2013 in “Canadian Medical Association Journal” Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.
5 citations
,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” Experts advise using sunscreen and proper skin care before, during, and after procedures to speed healing, prevent complications, and reduce scarring.
1 citations
,
August 2024 in “European Journal of Medicinal Chemistry Reports” Cosmetic microneedles are promising for precise treatments but face challenges like skin damage and regulations.
Reprogramming adult fibroblasts may enable scar-free healing.