The conclusion is that closing scalp wounds is possible, but restoring hair without donor material is still a major challenge.
328 citations
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
7 citations
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June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
3 citations
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October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
1 citations
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December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
March 2026 in “Research Square” Polymer dot nanozymes and exosomes, with laser stimulation, speed up wound healing.
19 citations
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August 2011 in “Facial Plastic Surgery Clinics of North America” Hair grafting is a key method for improving scars, especially in areas with hair, by transplanting hair to hide the scar while maintaining its original characteristics.
65 citations
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May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
38 citations
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December 2019 in “Iranian Biomedical Journal” Hair follicle stem cells help burns heal faster and stronger.
14 citations
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January 2021 in “Scientific Reports” Using micro skin tissue columns improves skin wound healing and reduces scarring.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
37 citations
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February 2019 in “Experimental Dermatology” Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.
22 citations
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February 2023 in “Heliyon” The hydrogel significantly speeds up wound healing and supports skin cell growth.
February 2026 in “BMC Plastic and Reconstructive Surgery” Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
147 citations
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November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
58 citations
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January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
43 citations
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January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
8 citations
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January 2020 in “Biomaterials Science” Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
January 1998 in “Lasers in Surgery and Medicine” Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.
11 citations
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June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
6 citations
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June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
113 citations
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June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
68 citations
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March 2019 in “Advanced Healthcare Materials” Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
4 citations
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August 2018 in “Journal of Cosmetic Dermatology” Wound tension after hair transplant surgery increases with strip size and is higher on the sides, affecting scarring.
72 citations
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
67 citations
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December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
46 citations
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September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.