research Microneedles as an Emerging Platform for Transdermal Delivery of Phytochemicals
Microneedles improve delivery of plant-based compounds through the skin, aiding treatments for hair loss, cancer, and wounds.
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research Commonalities Between COVID-19 and Radiation Injury
Some drugs may help treat both COVID-19 and radiation injury.
research Chronic overlapping pain conditions and nociplastic pain
Nociplastic pain is a complex, heritable trait with genetic links to chronic and neuropathic pain.
research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat
Researchers found WNT10A to be a key gene in developing goat hair follicles.
research Hair glucocorticoid levels in Parkinson’s disease
People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 -Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation
The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
research Tryptophan in human hair: correlation with pigmentation
Men have more tryptophan in their hair than women, and it increases with age and is higher in darker and grey or white hair.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Use of pegvaliase in the management of phenylketonuria: Case series of early experience in US clinics
Pegvaliase effectively reduces blood phenylalanine levels in most PKU patients, but requires personalized plans and good communication to manage side effects.
research Update on the therapeutic role of metformin in the management of polycystic ovary syndrome: Effects on pathophysiologic process and fertility outcomes
Metformin helps manage PCOS by improving fertility and is safe for pregnancy, especially when combined with certain treatments.
research Childhood urbanicity and hair steroid hormone levels in ten-year-old children
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants
Serotonergic antidepressants can significantly increase the risk of erectile dysfunction and have a small risk of causing irreversible sexual dysfunction.
research Proopiomelanocortin (POMC) and Psychodermatology
Psychological stress can worsen skin conditions like psoriasis and acne.
research A comment on the post-finasteride syndrome
The true incidence of post-Finasteride syndrome is unclear, and more research is needed.
research Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour
Early neurosteroid changes can alter adult brain function and behavior.
research The burden of alopecia areata: A scoping review focusing on quality of life, mental health and work productivity
Alopecia areata greatly affects people's life quality, mental health, and work life.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Sex-limited chromosomes and non-reproductive traits
Sex-limited chromosomes can affect traits not related to reproduction.
research Effects of Nursing Intervention Based on Health Belief Model on Self‐Perceived Burden, Drug Compliance, and Quality of Life of Renal Transplant Recipients
HBM-based nursing intervention improved medication compliance, reduced negative emotions, and enhanced quality of life for renal transplant recipients.
research Lifetime incidence and healthcare disparities in alopecia areata: a UK population-based cohort study
Alopecia areata affects 1 in 50 people, with non-White ethnic groups experiencing the most impact on mental health and work.
research Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome
Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
research Low-Molecular-Weight Synthetic Antioxidants: Classification, Pharmacological Profile, Effectiveness and Trends
Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
research Sex Differences in Animal Models of Sodium-Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence
Male mice are more susceptible to autism-like changes from valproic acid than female mice.
research Epiregulin promotes hair growth via EGFR‐medicated epidermal and ErbB4‐mediated dermal stimulation
Epiregulin can help hair grow and may be useful for treating hair loss.
research Repetitive Transcranial Magnetic Stimulation for Treatment of Trichotillomania: Case Series
rTMS may help treat trichotillomania in some patients.
research Intramembrane Proteolysis of Astrotactins
Astrotactin-2 is cleaved in a specific way that helps understand its maturation.
research Diagnostic delay, comorbid hidradenitis suppurativa and the prognostic value of bacterial culture in folliculitis decalvans: A cohort study
Educating dermatologists and screening for related conditions are crucial for treating folliculitis decalvans effectively.