Search

for
Search:

Sort by

Research

390-420 / 1000+ results

research 304 Sephardic Ancestry in Recessive Dystrophic Epidermolysis Bullosa Individuals Carrying the Prevalent c.6527insC Mutation

November 2022 in “Journal of Investigative Dermatology”

Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.

research Follicles, fungi and scalp conditions

1 citations , September 2011 in “British Journal of Dermatology”

Malassezia yeast plays a key role in dandruff and seborrhoeic dermatitis.

research Interfacial Adipose Tissue in Systemic Sclerosis

23 citations , January 2017 in “Current Rheumatology Reports”

Unique fat cells near fibrotic areas contribute to systemic sclerosis progression.

research 43755 Rapid Reduction and Strict Complete Response in Itch With Oral Difelikefalin in Subjects With Notalgia Paresthetica and Moderate-to-Severe Pruritus

September 2023 in “Journal of the American Academy of Dermatology”

Oral difelikefalin significantly reduces itch in notalgia paresthetica.

research ODP398 A Novel NR5A1 Gene Mutation Causing 46, XY DSD Without Adrenal Insufficiency in an Immigrant Boy from Dominican Republic

November 2022 in “Journal of the Endocrine Society”

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

research 1H NMR-based lipidomics of rodent fur: species-specific lipid profiles and SCD1 inhibitor-related dermal toxicity

5 citations , April 2014 in “Journal of Lipid Research”

SCD1 inhibitors can cause skin issues in rodents.

research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing

July 2024 in “Journal of Investigative Dermatology”

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

research Design, optimization, and in vitro characterization of fastdissolving tablets of nifedipine using response surface methodology

June 2026 in “International Journal of Drug Delivery Technology”

The study focused on developing fast-dissolving tablets (FDTs) of nifedipine, a poorly water-soluble antihypertensive agent, using a spray-drying approach and response surface methodology for optimization. The optimized tablets demonstrated rapid disintegration in less than 120 seconds, reduced wetting time, and enhanced dissolution profiles. The solubility of nifedipine was significantly improved in ethanol compared to aqueous media. The design of experiments (DoE) models indicated statistically significant effects of formulation variables on the tablets' performance. Solid-state studies confirmed the compatibility of the drug with excipients. Overall, the study successfully developed nifedipine FDTs with improved in vitro performance, suggesting their potential for better oral delivery.

research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

20 citations , October 2017 in “Stem Cell Reports”

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

research Nonscalp hair infection caused by Microsporum canis in patient with acquired immunodeficiency syndrome

10 citations , May 1991 in “Journal of the American Academy of Dermatology”

research Pilotropic Mycosis fungoides

11 citations , January 1999 in “Dermatology”

46,XY Disorders of Sex Development Due to Type 2 5-Alpha Reductase Deficiency in Three Siblings: A Case Report from a Low-Resource Setting

research Disorders of sex development (DSD) 46.XY due to type 2 5-α reductase deficiency in three siblings: Case report from a low-resource setting

September 2022 in “Annals of medicine and surgery”

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

research LIGA R and D and prototyping[Lithography, Electroforming, and Assembly]

July 1999 in “Journal of the American Academy of Dermatology”

Optimization and Characterization of a Focal Dermal Hypoplasia Mouse Model to Test Potential Treatments

research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

research 876 Imaging nanoscale changes in desmosome protein organization

April 2018 in “Journal of Investigative Dermatology”

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

research The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal–Epidermal Junction of Mouse Skin

1 citations , April 2023 in “International journal of molecular sciences”

Certain skin proteins can form anchoring structures without the protein AMACO.

research Investigation of hair shaft in seborrheic dermatitis using atomic force microscopy

17 citations , January 2011 in “Skin Research and Technology”

Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.

research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat

28 citations , October 2004 in “Differentiation”

A gene deletion causes the "hairless" trait in Iffa Credo rats.

A Model System for Long-Term Serum-Free Suspension Organ Culture of Human Fetal Tissues: Experiments on Digits and Skin from Multiple Body Regions

research A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions

17 citations , January 1997 in “Cell and Tissue Research”

Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.