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Colorectal cancer cells can adapt without losing their traits or drug sensitivity.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

A new mutation in the DCAF17 gene was found in a Chinese family, causing Woodhouse-Sakati syndrome and diabetes.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

A new green method accurately measures finasteride and tadalafil in drugs and plasma.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

Four bacteria from the lab were found to be resistant to selenium.

Blocking CXXC5 speeds up diabetic wound healing by improving blood vessel growth and skin repair.

A new fluorescent material can detect dextran sulfate sodium, turning green when present, useful for forensic and environmental monitoring.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

Dandelion-derived carbon dots effectively kill bacteria and speed up wound healing.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

Only one K16 gene on chromosome 17 makes a functional keratin protein.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

A new mouse mutation causes skin and hair defects due to a gene change.