research Structure and Development of the Skin and Cutaneous Appendages
Understanding skin structure and development helps diagnose and treat skin disorders.
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research 1329 Transglutaminase 2 deficiency leads to lipid accumulation and reduced autophagy in SZ95 sebocytes
Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.
research Comparison of artificial sebum with human and hamster sebum samples
Artificial sebum L closely mimics human sebum for drug delivery research.
research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors
Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
research A systematic method for the sensitive and specific determination of hair lipids in combination with chromatography
A new method accurately measures hair lipids, revealing individual differences.
research Epithelial stem cells and implications for wound repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research Applications and limitations of lipid nanoparticles in dermal and transdermal drug delivery via the follicular route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
research TGFβ signaling regulates lipogenesis in human sebaceous glands cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Acne, the Skin Microbiome, and Antibiotic Treatment
Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.
research Embryology, Histology, and Physiology of the Hair Follicle
The document explains how hair follicles develop, their structure, and how they grow.
research EEMCO Guidance for the in vivo Assessment of Skin Greasiness
The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages
Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream
The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.
research Testosterone therapy in men: Clinical and pharmacological perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Abstracts
Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.
research Inhibition of lipogenesis and sebum secretion for Lotus corniculatus seed extract in vitro and in vivo
Lotus corniculatus seed extract reduces oily skin by decreasing sebum production.
research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance
SCD1 is crucial for skin health and overall energy balance.
research A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health
Sebum is essential for skin health but can cause acne if unbalanced.
research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier
TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
research Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches
Improving skin barrier function is crucial for better acne treatment.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Prolactin as a candidate sebotrop(h)ic hormone?
Prolactin may influence skin glands and could be a target for treating acne and skin aging.
research Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis
Ceramide Synthase 4 is crucial for healthy skin barrier function.
research Comparative overview of phytoconstituents and pharmacological potential of Trigonella foenum-graecum leaves and seeds
Fenugreek seeds help with diabetes and cholesterol, while leaves fight microbes and dandruff.
research Oral retinoids-present status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research External lipid function in ethnic hairs
African hair has the most lipids, while Caucasian hair is more hydrated and stronger.
research Prevention of lipid loss from hair by surface and internal modification
Surface and internal treatments can help prevent hair lipid loss during washing.
research Integral hair lipid in human hair follicle
Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
research In vivo penetration of bare and lipid-coated silica nanoparticles across the human stratum corneum
Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.