June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
14 citations
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October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
13 citations
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January 2021 in “Histochemistry and Cell Biology” Cholesterol transport in hair follicles decreases from growth to regression phase.
222 citations
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January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
137 citations
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January 2000 in “Skin Pharmacology and Physiology” The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.
127 citations
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January 2013 in “PLOS ONE” Probiotic bacteria improved skin and hair health in aged mice.
85 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.
research Acne
81 citations
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January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
78 citations
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October 2020 in “Experimental Dermatology” Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
62 citations
,
July 2018 in “Lasers in Medical Science” LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.
59 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
51 citations
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July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
43 citations
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September 2012 in “International Journal of Dermatology” Hormonal therapies are safe and effective for treating adult women's acne.
34 citations
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October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
28 citations
,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
22 citations
,
January 2002 in “Treatments in endocrinology” Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
21 citations
,
July 2014 in “Clinics in Dermatology” Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.
17 citations
,
June 2017 in “Journal of pharmaceutical sciences” Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
17 citations
,
December 2015 in “International Journal of Cosmetic Science” Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
10 citations
,
January 2020 in “Advances in Dermatology and Allergology” Lower ghrelin levels and certain gene variations may increase acne risk.
9 citations
,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
6 citations
,
November 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
6 citations
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January 2011 in “Springer eBooks” Nutrition is important for skin health, and changing diet can help prevent and treat skin diseases.