35 citations
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December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
28 citations
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May 2018 in “Scientific reports” Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
27 citations
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February 2014 in “Planta Medica” Scutellaria baicalensis extract and baicalin may help prevent hair loss.
25 citations
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August 2014 in “Endocrinology” Researchers created a mouse model of a type of rickets that does not cause hair loss.
22 citations
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February 2008 in “Journal of Neurochemistry” Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
22 citations
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March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
19 citations
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November 2012 in “BJUI” Left-handed men experience more sexual side effects from finasteride treatment.
17 citations
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June 2021 in “Molecules” Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
16 citations
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December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
15 citations
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November 2023 in “Supportive Care in Cancer” Dermocosmetics help manage skin issues in cancer patients, improving outcomes and reducing treatment interruptions.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
13 citations
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June 2020 in “Journal of Dermatological Treatment” Topical finasteride helps regrow hair and reduce hair loss in men and women.
13 citations
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August 2013 in “Journal of pharmaceutical sciences” Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
13 citations
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November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
13 citations
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January 1999 in “Postgraduate Medicine” New drugs for rheumatoid arthritis show improvement but have side effects and are not a cure.
12 citations
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January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
11 citations
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August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
11 citations
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September 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
11 citations
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September 1999 in “Journal of the European Academy of Dermatology and Venereology” Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
9 citations
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December 2020 in “Dermatologic Therapy” Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
9 citations
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July 2014 in “Experimental Dermatology” PTHRP agonists can stimulate hair growth, especially in damaged follicles, while antagonists may initially increase growth but ultimately inhibit it.
6 citations
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January 2024 in “ACS Medicinal Chemistry Letters” Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.
6 citations
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December 2021 in “Scientific Reports” Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
6 citations
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January 1996 in “Endocrine-related Cancer” Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
4 citations
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June 2020 in “British Journal of Pharmacology” Activating TRPV4 in skin cells helps regrow hair in mice, possibly offering a treatment for hair loss.
3 citations
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September 2020 Dyclonine can effectively reduce skin issues by inhibiting the TRPV3 channel.
3 citations
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September 2020 in “Bladder cancer” 5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
3 citations
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November 2014 in “Protein Expression and Purification” Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
2 citations
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November 2019 in “Cancer reports” The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
2 citations
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February 2018 in “InTech eBooks” PCOS is complex, affects many, and requires informed management and lifestyle changes.