949 citations
,
January 2001 in “Cell” Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
New insights into cell communication in psoriasis suggest innovative drug treatments.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
6 citations
,
April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
May 2025 in “Proceedings of the National Academy of Sciences” UTX is crucial for skin differentiation and health, especially in females.
26 citations
,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
10 citations
,
January 2013 in “Regenerative Medicine Research” Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
854 citations
,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
August 2022 in “Metabolites” Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
52 citations
,
October 2005 in “Journal of Investigative Dermatology” Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.
10 citations
,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
September 2024 in “Journal of Inflammation Research” Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.
3 citations
,
March 2024 in “iScience” Long-lived proteins may predict age-related diseases.
517 citations
,
February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
12 citations
,
August 2022 in “Biochemical Journal” Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
2 citations
,
June 2023 in “Pharmaceutics” Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
153 citations
,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
127 citations
,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
April 2018 in “Journal of Investigative Dermatology” Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
8 citations
,
May 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.
9 citations
,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
March 2017 in “InTech eBooks” Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
36 citations
,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
12 citations
,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
6 citations
,
January 2016 in “Dermatology Review” Stem cells show promise for treating skin conditions and aiding healing.
61 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Beta-catenin is crucial for skin cell growth, development, and cancer formation.
375 citations
,
February 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
103 citations
,
January 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
22 citations
,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.